alexa In vivo Laser Scanning Confocal Microscopy Used in Herpes Simplex Keratitis Research
ISSN: 2155-9570

Journal of Clinical & Experimental Ophthalmology
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Research Article

In vivo Laser Scanning Confocal Microscopy Used in Herpes Simplex Keratitis Research

Xia Yuan*, Huang Zhen Ping, Shi Yu Hua and Yang Li Ping
Department of Ophthalmology, Jinling Hospital, School of Medicine, Nanjing University, Jiangsu, China 210002
Corresponding Author : Xia Yuan
Department of Ophthalmology
Jinling Hospital, 305# Zhong Shan East Road
Nanjing, Jiangsu, China (210003)
Tel: 0086-13913979022
E-mail: [email protected]
Received May 29, 2012; Accepted June 30, 2012; Published July 05, 2012
Citation: Yuan X, Ping HZ, Hua SY, Ping YL (2012) In vivo Laser Scanning Confocal Microscopy Used in Herpes Simplex Keratitis Research. J Clin Exp Ophthalmol 3:230. doi:10.4172/2155-9570.1000230
Copyright: © 2012 Yuan X, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Abstract

In vivo Laser Scanning Confocal Microscopy (LSCM) is a new technology that can be used to observe morphologic changes of the cornea on a cellular level. Non-invasive, high-contrast in vivo images of the cornea at different depths can be reliably and rapidly captured by LSCM. The high resolution of corneal structures, close to 1 μm, demonstrates the sensitivity of this technique, and the images can be stored for further research. The amount of magnification is high enough to visualize individual cells. In vivo images of the cornea at different depths from the epithelium to the endothelium are obtained immediately, directly and reproducibly. The in vivo laser scanning confocal microscopy is useful in HSK (Herpes Simplex Keratitis) research because it provides a new way to observe HSK and provides a new path for treatment.

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