Incidence and Risk Factors for Follow-Up Interruption of HIV-Infected Patients in Guadeloupe
- *Corresponding Author:
- Narcisse Elenga
Service de Pédiatrie
Centre hospitalier de Cayenne
Andrée Rosemon, Rue des Flamboyants
BP 6006-97306 Cayenne cedex, Guyane Française
E-mail: [email protected]
Received Date: July 30, 2013; Accepted Date: August 28, 2013; Published Date: September 03, 2013
Citation: Elenga N, Georger-Sow M-T, Messiaen T, Lamaury I, Favre I, et al. (2013) Incidence and Risk Factors for Follow-Up Interruption of HIV-Infected Patients in Guadeloupe. J AIDS Clin Res 4:238. doi:10.4172/2155-6113.1000238
Copyright: © 2013 Elenga N, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Background: Guadeloupe is the region of France with the second highest prevalence of HIV. Methods: To determine the risk factors for being lost to follow-up (LFU), a retrospective cohort study of 2,732 patients followed between 1988 and 2009 was conducted, and determined which variables were related to being LFU, i.e. permanently disappearing from HIV clinics or coming back after more than one year of missed appointments. Results: The incidence rate for permanent follow-up interruption was 9 per 100 person-years (8.3-9.7 personyears). The median time of LFU was 6.4 years (interquartile range 3-16.9 years). Cox modelling showed that the younger age groups (HR: 1.60[1.30-2.10], p=0.000) and patients diagnosed before 1997 (HR: 4.80[3.50-6.50], p=0.000) were significantly more likely to be permanently LFU. However, patients treated with HAART had a lower risk of being LFU (HR: 0.63[0.51-0.80], p=0.000). Conclusion: These results suggest that some patients may have died. They also allow to quantify the magnitude of a major yet often under-recognized problem and to identify its predictors in the context of Guadeloupe. This could help clinicians improve patient retention.