alexa Inert Cellulose Powder in the Treatment of Seasonal Allergic Rhinitis
ISSN: 2161-105X

Journal of Pulmonary & Respiratory Medicine
Open Access

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Inert Cellulose Powder in the Treatment of Seasonal Allergic Rhinitis

Minov JB1*, Karadzinska-Bislimovska J1, Petrova T2, Vasilevska K3, Stoleski SB1 and Mijakoski D1

1Institute for Occupational Helath of R. Macedonia, Skopje-WHO Collaborating Center, Skopje, Republic of Macedonia

2Department of Pharmacy Practice, Chicago State University, Chicago, USA

3Institute for Epidemiology and Biostatistics, Skopje, Republic of Macedonia

*Corresponding Author:
Jordan B Minov
Department of Cardiorespiratory Functional Diagnostics
Institute for Occupational Health of R. Macedonia,
WHO Collaborating Center and GA2LEN Collaborating Center
II Makedonska Brigada 43, 1000-Skopje
Republic of Macedonia
Tel: +389-2-2639-637
Fax: +389-2- 2621-428
E-mail: [email protected]

Received date: October 27, 2016; Accepted date: January 23, 2017; Published date: January 27, 2017

Citation: Minov JB, Karadzinska-Bislimovska J, Petrova T, Vasilevska K, Stoleski S, et al. (2017) Inert Cellulose Powder in the Treatment of Seasonal Allergic Rhinitis. J Pulm Respir Med 6: 388. doi: 10.4172/2161-105X.1000388

Copyright: ©2017 Minov JB, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Objective: To assess efficacy and safety of inert cellulose powder (ICP) in the treatment of mild seasonal allergic rhinitis (SAR). Methods: An observational, non-randomized, open study including 74 examinees suffering from mild SAR was conducted. The study subjects were divided in two groups, Group 1 (G1) and Group 2 (G2). The study subjects from G1 were treated 10 days with oral cetirizine and ICP, while the study subjects from G2 were treated 10 days only with oral cetirizine. The treatment outcomes were evaluated after five and 10 days by self-assessment of the symptoms on a five-point scale. Results: In both groups improvement of the symptoms five and 10 days after the treatment was registered. There was significantly higher prevalence of the G1 study subjects in the point 4 (“major relief, casual sneezing”) five days after beginning of the treatment (43.2% vs. 18.9%; P<0.05), as well as in the point 5 (“complete relief, without symptoms”) at the end of the treatment (56.7% vs. 27.0%; P<0.05). A low frequency of adverse effects was registered among examinees of both groups. Conclusion: The results obtained indicated high efficacy and safety of ICP in the treatment of mild SAR.


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