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Influence of Clove Tea (<em>Syzygium Aromaticum</em>) on Body Weight and Biochemical Parameters of Rats Subjected to Ethanol Consumption and Abstinence | Abstract
ISSN: 2161-0444

Medicinal Chemistry
Open Access

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Research Article

Influence of Clove Tea (Syzygium Aromaticum) on Body Weight and Biochemical Parameters of Rats Subjected to Ethanol Consumption and Abstinence

Fernanda Mani1*, Camila Pereira Braga1, Ethel Lourenzi Barbosa Novelli1 and José Maurício Sforcin2

1Departamento de Química e Bioquímica, Instituto de Biociências, UNESP, Campus de Botucatu. Distrito de Rubião Junior, s/n, CEP 18600-000, Botucatu-SP, Brasil

2Departamento de Microbiologia e Imunologia, Instituto de Biociências, UNESP, Campus de Botucatu. Distrito de Rubião Junior, s/n, CEP 18600-000, Botucatu-SP, Brasil

*Corresponding Author:
Fernanda Mani
Departamento de Química e Bioquímica - Instituto de Biociências – UNESP
Botucatu, São Paulo, Brazil
Tel: + 55 (14) 3811-6255
E-mail: [email protected]

Received date: April 26, 2012; Accepted date: May 19, 2012; Published date: May 24, 2012

Citation: Mani F, Braga CP, Barbosa Novelli EL, Sforcin JM (2012) Influence of Clove Tea (Syzygium Aromaticum) on Body Weight and Biochemical Parameters of Rats Subjected to Ethanol Consumption and Abstinence. Med chem 2:081-085. doi:10.4172/2161-0444.1000119

Copyright: © 2012 Mani F, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Clove has a large number of therapeutic properties and its tea has been used by the general population as antiinflammatory, antihyperglycemic, antimutagenic, bactericidal, and nematicidal, among others. Thus, the aim of this study was to assess the effect of clove on biochemical parameters of rats subjected to ethanol consumption and abstinence. The animals were subjected to ethanol intake before and after treatment with clove tea, according to their groups, as follows: GW received water (control); GE received 3% ethanol alone; GC received clove alone; GCE received clove for 7 consecutive days followed by 3% ethanol for 16 consecutive days; GEC received 3% ethanol for 16 consecutive days followed by clove for 7 consecutive days. Administration of clove tea alone or ethanol alone did not change serum parameters such as glucose, triglycerides, total cholesterol, total protein and albumin, and it did not alter weight gain although there was a significant difference in mean food consumption, which suggests that under such conditions clove tea or ethanol does not interfere with these parameters. On the other hand, administration of clove tea before or after ethanol administration led to significant changes in several parameters such as glucose, triglycerides, cholesterol, total protein and albumin. The obtained results thus suggest that prolonged ethanol intake should be avoided when clove tea is consumed daily.

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