Inheritance in OCD in Moslems
- *Corresponding Author:
- Nahla N
Ain Shams University, Egypt
Tel: +20 2 26831474
E-mail: [email protected]
Received Date: November 02, 2015; Accepted Date: November 09, 2015; Published Date: December 23, 2015
Citation: Nahla N, Nader D, Mona R, Mahmoud E (2015) Inheritance in OCD in Moslems. J Ment Disord Treat 1:103. doi:10.4172/2471-271X.1000103
Copyright: © 2015 Nahla N, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
There is increasing evidence that obsessive-compulsive disorder (OCD) is mediated by genetic factors. Although the precise mechanism of inheritance is unclear, recent evidence has pointed towards the involvement of the serotonergic and dopaminergic systems in the disorder's development. Objectives: To examine the clinical profile of symptoms in obsessive compulsive patients and their first and second degree relatives. Subjects and Methods: This study was designed in the Institute of psychiatry, Ain Shams University Hospitals. After signing an informed consent form, all the subjects 23 patients and 19 relatives were diagnosed according to DSM-IV and Structured Clinical Interview for DSM-IV (SCID I) and General Health Questionaire for psychiatric morbidity. Severity of OCD symptoms was assessed using Yale-Brown Obsessive Compulsive Scale (Y-BOCS) Symptom analysis was done on four symptom factor levels and presenting symptoms. Results: Showed 15 OCD patients had positive family history of psychiatric illness. 19 of their relatives showed 11 had OCD, 6 had psychosis and 3 had depression. The most prevalent symptom in OCD patients and their relatives was washing compulsions and religious obsessions. Conclusion: Genetic factors account for most of OCD symptoms in patients diagnosed with the disorder. Environmental factors also play a role in how these symptoms are expressed by observational learning.