alexa Inhibition of Bacterial Quorum-Sensing by Ferula asafoe
ISSN: 2169-0111

Advancements in Genetic Engineering
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Inhibition of Bacterial Quorum-Sensing by Ferula asafoetida Essential Oil

Pinakin Khambhala1, Shailja Verma1, Sanjay Joshi1, Sriram Seshadri2 and Vijay Kothari2*
1National Foods - THe Hing Research Center, GIDC-Waghodia, Vadodara, India
2Institute of Science, Nirma University, Ahmedabad, India
*Corresponding Author : Vijay Kothari
Institute of Science
Nirma University
Ahmedabad, India
Tel: +91-09998365230
E-mail: [email protected]
Rec date: April 24, 2016; Acc date: Apr 25, 2016; Pub date: Apr 27, 2016
Citation: Khambhala P, Verma S, Joshi S, Seshadri S, Kothari V (2016) Inhibition of Bacterial Quorum-Sensing by Ferula asafoetida Essential Oil. Adv Genet Eng 5:i105. doi:10.4172/2169-0111.1000i105
Copyright: © 2016 Khambhala P, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
 

Abstract

Pathogenic bacteria develop antibiotic-resistance at a pace much faster than the pace at which new antimicrobials can be discovered and introduced into the market. The process of new drug development demands identification of novel targets in the pathogenic population. Conventional antibiotics have largely targeted bacterial cell wall synthesis, protein synthesis, or nucleic acid synthesis. However in recent years, quorum sensing (QS) machinery of the pathogenic bacteria has received considerable attention as potential target of novel anti-infective agents.

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