alexa Initial Site of Crohn’s Disease is not an Independent Predictor of Outcome of Short Bowel Syndrome | OMICS International| Abstract

ISSN: 2476-1958

Journal of Inflammatory Bowel Diseases & Disorders

  • Research Article   
  • J Inflam Bowel Dis & Disor 2016, Vol 1(2): 112
  • DOI: 10.4172/2476-1958.1000112

Initial Site of Crohn’s Disease is not an Independent Predictor of Outcome of Short Bowel Syndrome

Wheeler MJ1, Langenfeld SJ1, Lyden E2, Weseman RA1, Rochling FA3 and Thompson JS1*
1Department of Surgery, University of Nebraska Medical Center, Omaha, USA
2College of Public Health, University of Nebraska Medical Center, Omaha, USA
3Department of Internal Medicine, University of Nebraska Medical Center, Omaha, USA
*Corresponding Author : Thompson JS, 983280 Nebraska Medical Center Omaha NE 68198-3280, USA, Tel: (402) 559-7182, Fax: (402) 559-6749, Email: [email protected]

Received Date: Oct 17, 2016 / Accepted Date: Oct 27, 2016 / Published Date: Nov 01, 2016

Abstract

Objective: Patients with Crohn's disease (CD) are at risk for Short Bowel Syndrome (SBS). Our aim was to determine the effect of initial site of disease on outcome in patients with CD developing SBS. Methods: We reviewed the outcome of 87 adult CD patients with SBS. Thirty-eight (44%) had initial ileocolonic disease, 27(31%) had colonic disease and 22(25%) had small intestinal disease. Results: Compared to patients with small intestinal and ileocolonic disease, patients with initial colonic disease were more likely to have a total colectomy (85% vs 32% and 37%, p<.05) and have an ostomy (89% vs 37% and 34%, p<.05). Intestinal remnant length was similar. Intestinal remnant length was the only predictor of need for longterm(> 1year) Parenteral Nutrition (PN) (p<0.0001). CD site at presentation was not significant on multivariate analysis (p=0.40). Conclusion: Patients with CD with colon as the initial site of disease who develop SBS have different anatomic characteristics. However, initial site of disease is not an independent predictor of need for long-term PN.

Keywords: Crohn’s disease; Short bowel syndrome; Intestinal resection; Intestinal failure; Crohn’s colitis

Citation: Wheeler MJ, Langenfeld SJ, Lyden E, Weseman RA, Rochling FA, et al. (2016) Initial Site of Crohn’s Disease is not an Independent Predictor of Outcome of Short Bowel Syndrome. J Inflam Bowel Dis & Disord 1: 112. Doi: 10.4172/2476-1958.1000112

Copyright: © 2016 Wheeler MJ, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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