alexa Innate Immune Response to the Dimorphic Fungal Pathogen Coccidioides: Molecular and Cellular Mechanisms | OMICS International
ISSN: 2155-9899

Journal of Clinical & Cellular Immunology
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Review Article

Innate Immune Response to the Dimorphic Fungal Pathogen Coccidioides: Molecular and Cellular Mechanisms

Angel González*
Basic and Applied Microbiology Research Group (MICROBA); Escuela de Microbiología, Universidad de Antioquia, Medellín, Colombia
Corresponding Author : Angel González
Basic and Applied Microbiology Research Group (MICROBA)
Universidad de Antioquia
Calle 67 No. 53-108, Office 5-103
Medellín, Colombia
Tel: 57-4-2198486
Fax: 57-4-2191007
E-mail: [email protected]
Received February 13, 2013; Accepted March 04, 2013; Published March 11, 2013
Citation:González A (2013) Innate Immune Response to the Dimorphic Fungal Pathogen Coccidioides: Molecular and Cellular Mechanisms. J Clin Cell Immunol S13:001. doi:10.4172/2155-9899.S13-001
Copyright: © 2013 González A. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Abstract

Coccidioides spp is considered to be one of the most important fungal pathogen of humans. It is the causal agent of coccidioidomycosis, a systemic and endemic mycosis with a significant impact on public health, mainly in the United States, Central and South America. The host innate immune system appears to play an important role in the initial interaction and recognition of Coccidioides infection and the subsequent development of adaptive immunity. In this review article, I focus on the interaction between the innate immune response and Coccidioides in an attempt to increase our knowledge of the pathogenesis of this fungus.

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