alexa In-Silico Identification of Novel Resistant Genes for Fungal Pathogen Fusarium oxysporum f. sp. cubense Race 4: Causative Agent of Banana Vascular Wilt Disease
ISSN: 2329-9029

Journal of Plant Biochemistry & Physiology
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Research Article

In-Silico Identification of Novel Resistant Genes for Fungal Pathogen Fusarium oxysporum f. sp. cubense Race 4: Causative Agent of Banana Vascular Wilt Disease

Shumaila Azam1,2,3*, Anum Munir1,2,3*, Muhammad Saad Khan2, Sahar Fazal2, Azhar Mehmood3, Sartaj Ali3 and Shahid Hussain2

1Bioinformatics International Research Club, Abbottabad, Pakistan

2Departments of Bioinformatics and Biosciences, Capital University of Science and Technology, Islamabad, Pakistan

3Department of Bioinformatics, Government Post Graduate College Mandolin, Abbottabad, Pakistan

*Corresponding Author:
Shumaila Azam
Bioinformatics International Research Club
Abbottabad, Pakistan
Tel: +923348958178
E-mail: [email protected]
 
Anum Munir
Bioinformatics International Research Club
Abbottabad, Pakistan
Tel: +923335852512
E-mail: [email protected]

Received date: December 22, 2016; Accepted date: January 03, 2017; Published date: January 09, 2017

Citation: Azam S, Munir A, Khan MS, Fazal S, Mehmood A, et al. (2017) In-Silico Identification of Novel Resistant Genes for Fungal Pathogen Fusarium oxysporum f. sp. cubense Race 4: Causative Agent of Banana Vascular Wilt Disease. J Plant Biochem Physiol 5: 175. doi: 10.4172/2329-9029.1000175

Copyright: © 2017 Azam S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Cavendish, the most widely grown banana cultivar, is relatively resistant to Race 1 of Fusarium oxysporum f. sp. cubense (Foc1) that caused widespread Panama disease during the first half of the 20th century but is susceptible to Tropical Race 4 of the Foc (Foc TR4), a threat to world banana production. Foc TR4 can spread into the vascular system of banana roots during the early infection process. The genome of the diploid species Musa acuminata; the ancestor of majority of the triploid banana cultivars has recently been sequenced. The identification for the resistant gene in this cultivar is a challenge for the researchers as the resistant gene against Foc4 has not been identified, the major focus of this research work was to identify the pathogenic genes and some resistant genes against those pathogenic genes, to get some better results for the laboratory work. The four resistant genes I, I-1, I-2, and I-3 were identified which provides resistance against Foc4 in banana. About three pathogenic genes SIX1 (SIX1A, SIX1B, SIX1C), SIX2, and SIX8 of Foc4 were identified. Out of these pathogenic genes SIX8 showed the greatest number of interactions with the resistant proteins. So it is proposed that I-1, I-2 and I-3 genes can be used in the further research work for providing better improvements of the resistive cultivars in banana.

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