alexa Insulin Use in Diabetic Hyperglycemic Emergencies: A Na
ISSN: 2155-6156

Journal of Diabetes & Metabolism
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Insulin Use in Diabetic Hyperglycemic Emergencies: A Narrative from Benin City, Nigeria

Ezeani Ignatius Ugochukwu1*, Chukwuonye Innocent Ijezie2, Okwuonu Godswill C2, Ohagwu Kenneth Arinze3, Abali Chuku4 and Eregie Aihanuwa5

1Division of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, Federal Medical Center, Umuahia, Abia state, Nigeria

2Division of Nephrology, Department of Internal Medicine, Federal Medical Center, Umuahia, Abia state, Nigeria

3Department of Internal Medicine, Federal Medical Center, Umuahia, Abia state, Nigeria

4Department of Ophthalmology, Federal Medical Center, Umuahia, Abia state, Nigeria

5Department of Internal Medicine, University of Benin Teaching Hospital, Benin City, Edo state, Nigeria

Corresponding Author:
Dr Ezeani IU (MBBS, FMCP)
Department of Medicine
Federal Medical Center, P.M.B 7001, Umuahia, Abia state, Nigeria
Tel: +2348060692131
E-mail: [email protected]

Received Date: June 26, 2015; Accepted Date: July 22, 2015; Published Date: July 27, 2015

Citation: Ugochukwu EI, Ijezie CI, Godswill CO, Arinze OK, Chuku A, et al. (2015) Insulin Use in Diabetic Hyperglycemic Emergencies: A Narrative from Benin City, Nigeria. J Diabetes Metab 6:585. doi:10.4172/2155-6156.1000585

Copyright: © 2015 Ugochukwu EI, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Objective: The primary objective of this study is to determine the types of hyperglycaemic emergencies (HEs) seen in UBTH. The secondary objective is to assess the amount of regular insulin used in various HEs within the first 24 hours to reduce hyperglycaemia (AI24HR), amount of regular insulin used in various HEs to reduce blood glucose level to less than 250 mg/dL (AITRH), and time (in hours) to resolve hyperglycaemia (TRH). Methodology: A total of 105 patients admitted to A&E unit for HEs were included in the study. This was a prospective, longitudinal study in which patients admitted to A&E unit who fulfilled the criteria for HEs were selected using a non-probability sampling technique. Data obtained was analyzed using SPSS version 15. Test statistics used were chi-squared test, student t-test and analysis of variance (ANOVA) while p-value was set at less than or equal to 0.05. Results: Types of HEs found in this study include diabetic ketoacidosis (DKA) seen in 28% of patients, hyperosmolar hyperglycaemic non ketotic state (HHNK) seen in 50%, normo-osmolar non ketotic hyperglycaemic state (NNHS) in 12%, and mixed diabetic ketoacidosis/hyperosmolar hyperglycaemic non ketotic state (DKA/HHNK) seen in 10% of patients. The mean (SD) AITRH in patients that presented with DKA, HHNK, NNHS and Mixed HE were 38.48 ± 15.40, 65.81 ± 15.88, 53.84 ± 15.48, 62.80 ± 12.26 units respectively. Similarly, the mean (SD) AI24HR in patients with DKA, HHNK, NNHS and Mixed HE were 73.17 ± 20.94, 113.4 ± 26.81, 88.31 ± 16.52, 103.0 ± 17.75 units respectively. The TRH in patients that presented with DKA, HHNK, NNHS and Mixed HE were 5.64 ± 4.7, 5.82 ± 3.1, 5.74 ± 2.7, 5.12 ± 2.24 hours respectively. There was statistically significant difference in AI24HR and AITRH in various types of HEs. However, there was no significant difference in TRH. Conclusion: Patients with HHNK constituted the highest number of subjects and they require more regular insulin than patients with other types of HEs.

Keywords

Share This Page

Additional Info

Loading
Loading Please wait..
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords