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ISSN: 0975-0851

Journal of Bioequivalence & Bioavailability
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Review Article

Integrated Application of Bioprocess Engineering and Biotechniques for Quality & Bulk Drug Manufacturing

Atanu Kumar Jena1*, D K Mahalakshmi2 and G Sridhari3

1Department of Biotechnology, Dr. M.G.R Educational & Research Institute, Dr. M.G.R University, Chennai-600095, India

2Department of Chemistry, KGRL College, Andhra University, Bhimavaram, A.P, India

3Department of Microbiology, D.N.R College, PG courses and Research center, Andhra University, Visakhapatnam, India

*Corresponding Author:
Dr. Atanu Kumar Jena
Department of Biotechnology
Dr. M.G.R Educational & Research Institute
Dr. M.G.R University,Chennai-600095, India
E-mail: [email protected]

Received Date: December 1, 2011; Accepted Date: December 24, 2011; Published Date: December 26, 2011

Citation: Atanu Kumar J, Mahalakshmi DK, Sridhari G (2011) Integrated Application of Bioprocess Engineering and Biotechniques for Quality & Bulk Drug Manufacturing. J Bioequiv Availab 3: 277-285. doi: 10.4172/jbb.1000099

Copyright: © 2011 Atanu Kumar J, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

One of the major challenges facing the pharmaceutical industry today is finding new ways to increase productivity, decrease costs whilst still ultimately developing new therapies that enhance human health. Both Biotechniques & Bioprocess engineering are integrated for bulk drug manufacturing of biopharmaceutical products to outcome the above problem. Different biotechnological processes are used in industries for large scale production of biological products for optimization of yield and the quality of end product. Various recent developments in biotechniques and its collaborated work with bioprocess engineering helps to maintain the quality in manufacturing process. However in this review article, we systemically describe all the techniques and different bioprocess used for manufacturing of drugs. To the author’s knowledge this review represents the most exhaust description of different biotechniques, different bioprocess, process development and design criteria in bioprocess.

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