Interest of Topical Corticosteroid Therapy in Immune Reconstitution Inflammatory Syndrome (IRIS) in HIV Infected Subjects: Case of the Genital Herpes
Patrice Ildevert Gbery, Ecra Elidjé*, Celestin Kouadio Ahogo, Komenan Kassi, Alexandre kouame Kouassi and Isidore Yao Kouassi
*Department of Dermatology of the Teaching Hospital of Treichville, Abidjan Côte d’Ivoire
- *Corresponding Author:
- Ecra Elidjé Joseph
Department of Dermatology of the Teaching
Hospital of Treichville, Luriers 6B, 191 Abidjan
15 BP 4 Abidjan15, Cote D'ivoire
E-mail: [email protected]
Received Date: October 09, 2015 Accepted Date: November 17,2015 Published Datea: November 28,2015
Citation: Gbery PI, Elidjé E, Ahogo CK, Kassi K, Kouassi AK, Kouassi IY (2015) Interest of Topical Corticosteroid Therapy in Immune Reconstitution Inflammatory Syndrome (IRIS) in HIV Infected Subjects: Case of the Genital Herpes. J Clin Exp Dermatol Res 6:309. doi: 10.4172/2155-9554.10000309
Copyright: © 2015 Gbery PI, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction in any medium, provided the original author and source are credited.
The immune reconstitution inflammatory syndrome occurs during high active antiretroviral treatment (HAART) initiation.It can be the reactivation of an already acquired infectious pathology. It also may result from the exacerbation of a previous pathology such as the genital herpes. Analyzing two clinical cases, the authors showed diagnosis and therapeutic difficulties. In patients receiving HAART expression of chronic herpes can lead to misdiagnosis, therapeutic and inefficiency of HSV specific treatment. CD4 cell count contributes to diagnosis. In this inflammatory syndrome the authors also showed earliest healing of herpes genital ulcer when using 2 to 4 weeks of topical corticosteroid therapy.Therefore it improves the patients' quality of life.