alexa Intraoperative Radiation Therapy for Breast Cancer Not Associated with Pulmonary Complications
ISSN: 2155-9619

Journal of Nuclear Medicine & Radiation Therapy
Open Access

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Intraoperative Radiation Therapy for Breast Cancer Not Associated with Pulmonary Complications

David R. Kalos1,2, Mark E. Lund1,2, David P. Visco1, Mark Lewis1and Jeffrey B. Hoag1,2*

1Eastern Regional Medical Center, Cancer Treatment Centers of America, 1331 E Wyoming Ave, Philadelphia, PA 19124, USA

2Drexel University College of Medicine, 2900 W Queen Ln, Philadelphia, PA 19129, USA

*Corresponding Author:
Jeffrey B. Hoag
Director, Critical Care Medicine
Cancer Treatment Centers of America
Eastern Regional Medical Center
1331 East Wyoming Ave.; Suite
3170 Philadelphia, PA. 19125, USA
Tel: 215-537-4833
Fax: 215-537-7710
E-mail: [email protected]

Received date: September 30, 2014; Accepted date: November 06, 2014; Published date: November 10, 2014

Citation: Kalos DR, Lund ME, Visco DP, Lewis M, Hoag JB (2014) Intraoperative Radiation Therapy for Breast Cancer Not Associated with Pulmonary Complications. J Nucl Med Radiat Ther 6:198. doi: 10.4172/2155-9619.1000198

Copyright: © 2014 Kalos DR, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Radiation pneumonitis and radiation-induced cryptogenic organizing pneumonia are common complications after external beam radiation therapy following breast conserving surgery for patients with early stage breast cancer. Intraoperative radiation therapy (IORT) is designed to decrease radiation exposure to the lung, skin, soft tissue, and contralateral breast. A single-center, retrospective cohort of all patients receiving IORT between 2009 and 2013 was analyzed, and 122 cases of IORT were found. There were no instances of pulmonary complication in patients receiving IORT without whole breast irradiation. The only instance of radiation pneumonitis identified was in a patient who received subsequent external beam radiation after boost IORT. As there are no previous systemic evaluations of pulmonary complications of IORT, this study supports its reported safety.


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