Reach Us +1-947-333-4405
Intrathecal dexmedetomidine: Useful or not? | OMICS International | Abstract
ISSN: 2155-6148

Journal of Anesthesia & Clinical Research
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Intrathecal dexmedetomidine: Useful or not?

Sherif A Abdelhamid* and Mohamed H El-lakany

Lecturer of Anaesthesia and Surgical Intensive Care-Medical Research Institute-Alexandria University, Egypt

*Corresponding Author:
Sherif A Abdelhamid
Lecturer of Anaesthesia and
Surgical Intensive Care-Medical Research Institute-Alexandria University, Egypt
E-mail: [email protected]

Received Date: July 22, 2013; Accepted Date: September 27, 2013; Published Date: September 30, 2013

Citation: Abdelhamid SA, El-lakany MH (2013) Intrathecal dexmedetomidine: Useful or not? J Anesth Clin Res 4:351. doi: 10.4172/2155-6148.1000351

Copyright: © 2013 Abdelhamid SA, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Spinal anesthesia is used commonly intra operatively. However, local anesthetics are associated with relatively short duration of action. A number of adjuvants have been used to prolong the postoperative analgesia.

Objectives: To evaluate role of dexmedetomidine added to heavy bupivacaine 0.5% intrathecally for lower abdominal surgeries. Subjects and methods: Sixty two patients were randomly divided into one of two group, Group (D) received 3.5 mL volume of 0.5% hyperbaric bupivacaine and 5 μg dexmedetomidine in 0.5 mL of preservative free normal saline intrathecally. Group (P) received 0.5 ml normal saline added to the same dose of heavy 0.5% bupivacaine and served as placebo.

Results: There was significantly less time needed to reach T8 sensory level, 2-segment regression, and time to reach Bromage 3in group (D) compared to group (P). There was significantly more time needed for first requirement of analgesia in group (D) compared to group (P). There was a significantly less analgesic dose requirement in group (D) compared to group (P).

Conclusion: Receiving Dexmedetomidine at a dose of 5 μg provides earlier sensory and motor blockade, less postoperative analgesic requirements, less shivering among patients of lower abdominal surgery under intrathecal anaesthesia with no sedation effect or neurologic complications.


Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2019-20
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri and Aquaculture Journals

Dr. Krish

[email protected]

+1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals


[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

ankara escort

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

pendik escort

[email protected]

1-702-714-7001Extn: 9042

© 2008- 2019 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version