alexa Invasive Molar Pregnancy in a Woman Aged 54 Years A Cas
ISSN: 2165-7920

Journal of Clinical Case Reports
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Case Report

Invasive Molar Pregnancy in a Woman Aged 54 Years A Case Report

Cringu Antoniu Ionescu1,2*, Mariana Bragaru2, Iulia Maria Tarcomnicu2, Camelia Teodora Vladescu3 and Mihai Dimitriu1
1Department of Obstetrics and Gynaecology, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
2Department of Obstetrics and Gynaecology, “St. Pantelimon” Clinical Emergency Hospital, Bucharest, Romania
3Department of Pathology, “St. Pantelimon” Clinical Emergency Hospital, Bucharest, Romania
*Corresponding Author : Cringu Antoniu Ionescu
MD, PhD, Department of Obstetrics and
Gynaecology, Associate Professor
University of Medicine Carol Davila, Bucharest, Romania
Tel: +40213180862
E-mail: [email protected]
Received January 31, 2016; Accepted March 08, 2016; Published March 13, 2016
Citation: Ionescu CA, Bragaru M, Tarcomnicu IM, Vladescu CT, Dimitriu M (2016) Invasive Molar Pregnancy in a Woman Aged 54 Years A Case Report. J Clin Case Rep 6:733. doi:10.4172/2165-7920.1000733
Copyright: © 2016 Ionescu CA, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


We reported a 54-year-old patient with a complete hydatidiform mole invasive in myometrium. This diagnostic was suggested by irregular vaginal haemorrhage, amenorrhea and reduced nausea. Our paraclinical investigation was: pelvic ultrasound and level of serum beta-human chorionic gonadotropin (β-hCG). Endovaginal ultrasound reveal enlarged uterus volume, with dimensions 12/15/8 cm, with the presence of multiple nodular formations located intramural and subserosal and a mass with Doppler rich blood supply through myometrium and endometrium. The level of β-hCG was 28099.00 mIU/L. Therapeutic method applied was abdominal hysterectomy and bilateral salpingo-oophorectomy. Anatomopathological report revealed a complete invasive mole and endometrial polyp. After the surgical intervention the patient was treated with Methotrexate as prophylactic chemotherapy recommended by oncologists because of the invasive character of mole and age of patient. The complete invasive mole is a benign tumor that is characterized by abnormal proliferation of trophoblast and is locally invasive and possible metastatic. Developing pregnancy rate in perimenopause period is very rare and most of the pregnancies that occur at this age are abnormal, spontaneous abortion occurring most often. We choose to report this case to emphasize that this condition can occur in a relatively advanced age, especially during perimenopause period.


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