alexa Investigation and Characterization of Biologically Acti
ISSN: 2329-8901

Journal of Probiotics & Health
Open Access

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Research Article

Investigation and Characterization of Biologically Active Compounds Recovered from Kefir (A Probiotic Fermented Milk)

Sahar Abd El Moghethl,*, Ahmed Osama El-Gendy2, Serageldeen Sultan3 and Khalid A El-Nesr4

1Post Graduate Studies for Advanced Sciences, Beni-Suef University, Beni-Suef, Egypt

2Pharmacy, Microbiology and Immunology Department, Beni-Suef University, BeniSuef, Egypt

3Veterinary Medicine, Virology Division, Department of Microbiology, South Valley University, Qena, Egypt

4Veterinary Medicine, Department of Pathology, Beni-Suef University, Beni-Suef, Egypt

*Corresponding Author:
Sahar Abd El Mogheth
Post Graduate Studies for Advanced Sciences
Beni-Suef University, Beni-Suef, Egypt
Tel: +201020429455
E-mail: [email protected]

Received Date: April 17, 2017 Accepted Date: April 24, 2017 Published Date: April 29, 2017

Citation: Mogheth SAE, El-Gendy AO, Sultan S, El-Nesr KA (2017) Investigation and Characterization of Biologically Active Compounds Recovered from Kefir (A Probiotic Fermented Milk). J Prob Health 5: 173. doi: 10.4172/2329-8901.1000173

Copyright: © 2017 Madani S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Fermented milk is considered as a good source of nutrition for many people. One of the most important substances that could be used in milk fermentation is kefir grains. Kefir fermented milk is very important in many health conditions such as bacterial infections, high blood pressure and some hepatic conditions. The aim of this study was to determine the antibacterial activity of kefir fermented milk against some pathogenic microorganisms as Salmonella sp, Escherichia coli, Staphylococcus sp and Candida albicans by using disc diffusion method. The efficacy of kefir fermented milk was investigated as a hepato-protective against CCl4 inducing liver toxicity and as a protective agent against kidney and spleen damages using laboratory animal model. The results revealed that the kefir fermented milk had a potent antibacterial activity against all tested pathogenic isolates and it also showed high significant protection in mice against CCl4 toxicity. In conclusion, kefir milk can be used as an antibacterial supplement and as a protective agent against liver toxicity.


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