alexa In vitro Antibacterial and Anticancer Potential of CeO2

Journal of Nanosciences: Current Research
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Research Article

In vitro Antibacterial and Anticancer Potential of CeO2 Nanoparticles Prepared by Co-precipitation and Green Synthesis Method

Parvathya S1* and Venkatramanb BR2

1Department of Chemistry, Government Arts College (Autonomous), Salem, Tamil Nadu, India

2Department of Chemistry, Periyar E.V.R. College, Tiruchirappalli, Tamil Nadu, India

*Corresponding Author:
Dr. S Parvathya
Department of Chemistry
Government Arts College, Tamil Nadu, India
Tel: +919629019582
E-mail: [email protected]

Received Date: May 24, 2017; Accepted Date: June 12, 2017; Published Date: June 19, 2017

Citation: Parvathya S, Venatramanb BR (2017) In vitro Antibacterial and Anticancer Potential of CeO2 Nanoparticles Prepared by Co-precipitation and Green Synthesis Method. J Nanosci Curr Res 2: 111.

Copyright: © 2017 Parvathya S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Cerium oxide nanoparticles (CeO2 NPs) were synthesized through chemical (co-precipitation method) (C-CeO2 NPs) and green synthetic route (A. indica leaf extract) (G-CeO2 NPs) and comparative studies were also carried out in the first time. From the XRD Pattern of C-CeO2 and G-CeO2 NPs revealed that both were in cubic phase. The morphological and elemental compositions were identified by FESEM, TEM and EDAX spectra. The optical characterizations were carried out using UV-Visible and Photoluminescence spectral analysis. Further the FT-IR and FT-Raman analysis were also confirmed to formation of CeO2 nanoparticles. The oxidation states of the elements Ce (3d), C (1s) and O (1s) were confirmed by XPS studies. The green synthesized CeO2 NPs possessed a higher antibacterial activity than chemical CeO2 NPs. The cytotoxic effect of C-CeO2 and G-CeO2 NPs were analyzed in cultured (A549) human lung cancer cell line.

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