alexa Involvement of Varicose Veins in Superficial Venous Thr
ISSN: 2161-0940

Anatomy & Physiology: Current Research
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Short Communication

Involvement of Varicose Veins in Superficial Venous Thrombosis

Pavel Poredos*

University Medical Center Ljubljana, Slovenia

*Corresponding Author:
Pavel Poredos
University Medical Center, Ljubljana, Slovenia
Tel: +38615228032
E-mail: [email protected]

Received date: December 28, 2015 Accepted date: January 15, 2016 Published date: January 18, 2016

Citation: Poredos P (2016) Involvement of Varicose Veins in Superficial Venous Thrombosis. Anat Physiol 6:196. doi: 10.4172/2161-0940.1000196

Copyright: © 2016 Poredos P. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



 

Abstract

Varicose veins are usually a sign of a benign disease, however with progression of the disease and advanced age, they can lead to serious clinical problem. Beside chronic venous insufficiency, superficial venous thrombosis (SVT) represents one of the most frequent complications which can complicate with deep venous thrombosis (DVT) and pulmonary embolism. Classical risk factors for SVT are similar as for DVT. However, varicose veins represent one of the most important risk factors for the development of SVT. In varicose veins blood flow is usually turbulent, with increased shear stress which causes vascular damage, resulting in endothelial dysfunction and structural deterioration of vessel wall accompanied by inflammatory response. Because of changes in hemodynamic conditions, in varicose veins the constitution of blood is changed. In varicose veins haematocrit level is increased and consequently blood viscosity. Further, in the blood of varicose veins circulating inflammatory markers are increased, as well as circulating markers of endothelial damage. There is also imbalance between the pro-and anticoagulant factors and between pro-and antifibrinolytic agents favouring hypercoagulable microenvironment. Therefore, varicose veins represent the highest risk for development of SVT.

Keywords

Share This Page

Additional Info

Loading
Loading Please wait..
 
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords