alexa Iodine-131 Rituximab Radioimmunotherapy: Durable Control of Follicular Lymphoma
ISSN: 2155-9619

Journal of Nuclear Medicine & Radiation Therapy
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Iodine-131 Rituximab Radioimmunotherapy: Durable Control of Follicular Lymphoma

Paul C Kruger1, David JL Joske2 and Harvey Turner J 3*

1Department of Hematology, The Queen Elizabeth II Medical Center, Nedlands, Western Australia

2The University of Western Australia, Crawley, Western Australia

3Department of Nuclear Medicine, Fremantle Hospital and Health Service, Fremantle, Western Australia

*Corresponding Author:
Harvey Turner J
Director, Department of Nuclear Medicine
Fremantle Hospital and Health Service
Fremantle, Western Australia
Tel: 61 08 9431 2888
Fax: 61 08 9431 2889
E-mail: [email protected]

Received date: July 30, 2014; Accepted date: September 23, 2014; Published date: September 26, 2014

Citation: Kruger PC, Joske DJL, Turner JH (2014) Iodine-131 Rituximab Radioimmunotherapy: Durable Control of Follicular Lymphoma. J Nucl Med Radiat Ther 5:191. doi: 10.4172/2155-9619.1000191

Copyright: © 2014 Kruger PC, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Aims: We evaluated the response and toxicity, after long-term follow up of Iodine-131 rituximab radioimmunotherapy in patients with follicular lymphoma under the routine clinical care of a single hematologist over a period of 12 years.

Materials and methods: Patients received 131I-rituximab radioimmunotherapy according to a standard, personalized dosimetry protocol predicated upon a prescribed whole body radiation absorbed dose of 0.75Gy. Four doses of maintenance rituximab were subsequently administered over 12 months.

Results: Response rate was 97% with 24(77%) patients experiencing a complete remission confirmed on 18F-fluorodeoxyglucose positron emission tomography-computerized tomography scan. The cohort of 3 patients with duodenal lymphoma all achieved complete remission lasting 4-5 years.
Disclosure statement: There is no conflict of interest to declare with the publication of this work. No author has a financial incentive associated with the publication of this article.

Conclusion: 131I-rituximab radioimmunotherapy is an effective, safe, affordable, repeatable treatment which does not compromise future therapy options upon relapse. It is practical, being administered on an outpatient basis, and referring physicians maintain governance of their patients.


Share This Page

Additional Info

Loading Please wait..
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals


busine[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version