alexa Iron Overload in Two Children after Allogeneic Hematopoietic SCT with Concomitant HFE p.s65cgene Mutation | OMICS International | Abstract
ISSN: 2165-7831

Journal of Blood & Lymph
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Letter to Editor

Iron Overload in Two Children after Allogeneic Hematopoietic SCT with Concomitant HFE p.s65cgene Mutation

Barbara Kaczorowska-Hac1*, Magdalena Szalewska1, Maciej Niedzwiecki1, Elzbieta Adamkiewicz-Drozynska1 and Ewa Milosz2

1 Department of Pediatrics, Hematology and Oncology, Medical University of Gdansk, Poland

2 Laboratory of Molecular Biology, Medical University of Gdansk, Poland

*Corresponding Author:
Barbara Kaczorowska-Hac
Department of Pediatrics
Hematology, Oncology and Endocrinology
Medical University of Gdansk
Debinki 7 Str, 80-952 Gdansk, Poland
Tel: +48583492860
Fax: 48584392863
E-mail: [email protected]

Received Date: November 21, 2013; Accepted Date: January 08, 2014; Published Date: January 13, 2014

Citation: Kaczorowska-Hac B, Szalewska M, Niedzwiecki M, Adamkiewicz- Drozynska E, Milosz E (2014) Iron Overload in Two Children after Allogeneic Hematopoietic SCT with Concomitant HFE p.s65cgene Mutation. J Blood Lymph 4:117. doi: 10.4172/2165-7831.1000117

Copyright: © 2014 Kaczorowska-Hac B, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Acute Myelomonoblastic Leukaemia (ANLL M4) and Aplastic Anemia (AA) are rare childhood diseases. Treatment of ANLL involves chemotherapy and radiotherapy, while immunosuppressive therapy is used in the treatment of AA. In selected cases, both disorders can be treated by performing a Hematopoietic Stem Cell Transplantation (HSCT). In addition, supportive medical care which includes antibiotics, antifungal drugs, packed red cells and platelets, is usually essential due to adverse effects caused by the therapy. Herein, we present a 15- year- old boy with ANLL M4 and a 17- year- old girl suffering from Severe Aplastic Anemia (SAA) for 3 and 4 years respectively, in whom iron overload was noted after they had undergone allogeneic HSCT (allo HSCT). On further diagnosis, co-existence of S65C HFE gene carriage was identified in both of them.

Keywords

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version