alexa Iron Oxide Biomagnetic Nanoparticles (IO-BMNPs); Synthe
ISSN: 2157-7439

Journal of Nanomedicine & Nanotechnology
Open Access

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Review Article

Iron Oxide Biomagnetic Nanoparticles (IO-BMNPs); Synthesis, Characterization and Biomedical Application–A Review

Nochehdehi AR1*, Thomas S2, Sadri M3, Afghahi SSS4 and Mehdi Hadavi SM5

1Biomaterials Research Group, Biomedical Engineering Department, Materials and Biomaterials Research Center (MBMRC), Tehran, Iran

2Polymer Science & Engineering, School of Chemical Sciences and Hon. Director of International and Inter UniversityCentre for Nanoscience and Nanotechnology (IIUCNN), Mahatma Gandhi University (MGU), Kottayam, Kerala, India

3Department of Biochemistry and Biophysics, Education and Research Center of Science and Biotechnology, Malek Ashtar University of Technology, Tehran, Iran

4Materials Science and Engineering, Imam Hossein University, Department of Engineering, Babaei Highway, P.O. Box: 15816-18711, Tehran, Iran

5Materials and Biomaterials Research Center (MBMRC) and Iran National Institute of Materials and Energy (MERC), Tehran, Iran

*Corresponding Author:
Amirsadegh Rezazadeh
Nochehdehi, Fellow Researcher
Biomaterials Research Group
Biomedical Engineering Department
Materials and Biomaterials Research Center (MBMRC)
Tehran, Iran
Tel: 98-9128406846
E-mail: [email protected]

Received Date: December 21, 2016; Accepted Date: January 16, 2017; Published Date: January 23, 2017

Citation: Nochehdehi AR, Thomas S, Sadri M, Afghahi SSS, Mehdi Hadavi SM (2017) Iron Oxide Biomagnetic Nanoparticles (IO-BMNPs); Synthesis, Characterization and Biomedical Application – A Review. J Nanomed Nanotechnol 8: 423. doi: 10.4172/2157-7439.1000423

Copyright: © 2017 Nochehdehi AR, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Nanotechnology is a multidisciplinary branch of science which encompasses numerous diverse fields of science and technology, ranging from biomedical, pharmaceutical, agricultural, environmental, advanced materials, chemical science, physics, electronics, information technology, and so on. Physical and Chemical properties as a major advantages of Nanoparticles can be used in various applications from Industries to medicine. Besides, Magnetic nanoparticles for medical applications have been developed by many researchers. In recent decades, it has received attention by virtue of their potential for applications in different fields. Due to several advantages and widespread applications of magnetic Nanoparticles in biotechnology, medical, material science, engineering, and environmental areas, much attention has been paid to the synthesis of different kinds of Biomagnetic nanoparticles (BMNPs). Core-shell nanoparticles include of coated various materials like: biopolymers (Chitosan, PAA) and bioceramics (Hydroxyapatite) as a shell on top of them and different hard and soft materials like metal oxide (Iron oxide and Cob alt composite) as a core. Improved properties of core-shell nanoparticles like less cytotoxicity, increase biocompatibility, decrease in an interactions with biomolecules, increase physicochemical stability and sort of that, can be due to their use in biological applications. After reviewing several research and review articles and synthesis procedure of Iron based Bio-magnetic Nanoparticles (BMNPs), we should emphasize that, It can be used in different applications like magnetic resonance imaging (MRI), drug delivery systems (DDS), immunoassay, also specially in diagnosis and treatment of cancer via hyperthermia (heat therapy) method.


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