alexa Is Bacille Calmette-Guérin (BCG) Vaccine a Known Risk Factor for Latent Tuberculosis Infection?: A Cross-sectional Study on 180 New Immigrants from BCG-vaccinated Countries to Kuwait | Abstract
ISSN: 2157-7560

Journal of Vaccines & Vaccination
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Research Article

Is Bacille Calmette-Guérin (BCG) Vaccine a Known Risk Factor for Latent Tuberculosis Infection?: A Cross-sectional Study on 180 New Immigrants from BCG-vaccinated Countries to Kuwait

Adel AL-Harbie1*, Kim Picozzi1, Michael Thrusfield2, Ali Sadek3 and Susan C Welburn1

1Division of Pathway Medicine & Centre for Infectious Diseases, School of Biomedical Sciences, College of Medicine & Veterinary Medicine, The University of Edinburgh, Chancellor’s Building, 49 Little France Crescent, Edinburgh, EH16 4SB, UK

2Veterinary Clinical Sciences, Royal (Dick) School of Veterinary Studies. The University of Edinburgh, Easter Bush, EH25 9RG, UK

3Department of Public Health and Community Medicine, Faculty of Medicine, University of Alexandria, Egypt

*Corresponding Author:
Adel AL-Harbie
Division of Pathway Medicine & Centre for Infectious Diseases
School of Biomedical Sciences
College of Medicine & Veterinary Medicine
The University of Edinburgh, Chancellor‘s Building
49 Little France Crescent, Edinburgh, EH16 4SB, UK
E-mail: [email protected]

Received date: August 22, 2012; Accepted date: September 27, 2012; Published date: October 03, 2012

Citation: Harbie AA, Picozzi K, Thrusfield M, Sadek A, Welburn SC (2012) Is Bacille Calmette-Guérin (BCG) Vaccine a Known Risk Factor for Latent Tuberculosis Infection?: A Cross-sectional Study on 180 New Immigrants from BCG-vaccinated Countries to Kuwait. J Vaccines Vaccin 3:151. doi:10.4172/2157-7560.1000151

Copyright: © 2012 Harbie AA, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

The Bacelle Calmette-Guérin (BCG) vaccine has existed for 90 years and is the most widely used of all current national childhood immunization programmes. The impact of BCG vaccination on transmission of Mycobacterium tuberculosis is not clear or whether BCG confers lifelong immunity through sufficient protection against formation and diagnosis of latent tuberculosis infection (LTBI) is recently questionable especially in tuberculosis endemic regions and vaccinated high risk individuals, which was discussed along the paper work following a new evidence- based criteria for LTBI diagnosis.

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