alexa Is Saliva an Alternative Non-Invasive Sample for the Estimation of Protein Profile amongst Diabetics and Gender-based Diagnostics? | OMICS International | Abstract
ISSN: 2161-0940

Anatomy & Physiology: Current Research
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Is Saliva an Alternative Non-Invasive Sample for the Estimation of Protein Profile amongst Diabetics and Gender-based Diagnostics?

Agoro E 1*, Ebiere NE2, Eseimokumo SA3 and Odegbemi JO4

1Department of Chemical Pathology, Medical Laboratory Services, Federal Medical Center, Yenagoa, Bayelsa State, Nigeria

2Bayelsa State College of Health Sciences and Technology, Otuogidi, Bayelsa State, Nigeria

3Jasper Boro College of Education, Sagbama, Bayelsa State, Nigeria

4Comprehensive Health Centre, Gbongan, Osun State

*Corresponding Author:
Agoro E
Department of Chemical Pathology
Medical Laboratory Services
Federal Medical Center, Yenagoa
Bayelsa State, Nigeria
Tel: +08037434995
E-mail: [email protected]

Received Date: March 08, 2017; Accepted Date: March 20, 2017; Published Date: March 27, 2017

Citation: Agoro E, Ebiere NE, Eseimokumo SA, Odegbemi JO (2017) Is Saliva an Alternative Non-Invasive Sample for the Estimation of Protein Profile amongst Diabetics and Gender-based Diagnostics? Anat Physiol 7:255. doi: 10.4172/2161-0940.1000255

Copyright: © 2017 Agoro E, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Introduction: Protein profile is an important investigation utilized for the diagnosis and management of arrays of diseases such as diabetes mellitus. Нe measurement of protein profile is basically carried out through invasive sample blood which inflicts pain and is financiall\ cumbersome. Нe study is aimed at generating an alternative noninvasive sample such as saliva for proteins analysis. Materials and Methods: A total of 100 subjects were recruited for the study; 50 subjects diagnosed with type 2 diabetes mellitus and 50 apparently healthy control subjects. Protein profile incudes total protein, albumin, and globulin and albumin/ globulin ratio. Total protein and albumin were estimated using biuret and bromocresol green methods respectively. Globulin and albumin/globulin were estimated mathematically. Results: Нe study showed that there was no correlation (P>0.05) between saliva and serum protein profiles amongst controls and diabetes subjects. However, significant correlation (P<0.05) was observed for globulin and albumin/ globulin ratio for diabetic subject with glucose level above threshold level. A comparison between diabetics and controls showed a significant decrease (P<0.05) in serum total protein and globulin, while an increase for serum albumin/globulin ratio. Salivary protein profile and gender influence on serum and salivary protein profiles exhibited a non-significant diوٴerence (P<0.05). Conclusion: Нe findings showed that serum protein profiles is an important panel of laboratory investigation for the management of diabetes mellitus. Also, gender diوٴerence in customized diagnostics is of no clinical importance

Keywords

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version