alexa Isolated CNS Blast Crisis of CML in A Patient on Dasati
ISSN: 2329-6917

Journal of Leukemia
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Case Report

Isolated CNS Blast Crisis of CML in A Patient on Dasatinib Therapy

Rehab Al-blooshi1, Dimitrios Vergidis2 and Jeffrey H Lipton3*

1Department of Medical Oncology and Hematology, Princess Margaret Cancer Center, Toronto, Ontario, Canada

2Thunder Bay Regional Health Sciences Centre, Thunder Bay, Ontario, Canada

3Department of Medical Oncology and Hematology, Princess Margaret cancer center, Toronto, Ontario, Canada

*Corresponding Author:
Jeffrey Lipton
PhD, MD, Department of Medical Oncology and Hematology
Princess Margaret Cancer Centre, Toronto, Ontario, Canada
Tel: +1-416-946-2266
E-mail: [email protected]

Received date: May 07, 2016; Accepted date: June 09, 2016; Published date: June 13, 2016

Citation: Al-blooshi R, Vergidis D, Lipton JH (2016) Isolated CNS Blast Crisis of CML in A Patient on Dasatinib Therapy. J Leuk 4:212. doi:10.4172/2329-6917.1000212

Copyright: © 2016 Al-blooshi R, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

We report a case of a young male with chronic phase CML who despite achieving an excellent response to dasatinib therapy, developed isolated CNS blast crisis even though this tyrosine kinase inhibitor is the only one reported to cross the blood brain barrier.

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