alexa Isolation and Characterization of Constituents from the Leaves of Xanthium strumarium and their Evaluation for Antioxidant and Antimicrobial Potential
ISSN: 2329-6836

Natural Products Chemistry & Research
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Research Article

Isolation and Characterization of Constituents from the Leaves of Xanthium strumarium and their Evaluation for Antioxidant and Antimicrobial Potential

Mandeep Kaur1, Anjoo Kamboj1*, Aarti Rathour1 and Ajay Kumar Saluja2
1Chandigarh College of Pharmacy, Landran - 140307, Mohali, India
2A. R. College of Pharmacy, Vallabh Vidyanagar - 388120, Gujarat, India
Corresponding Author : Anjoo Kamboj
Chandigarh College of Pharmacy
Landran, Mohali-140307, Punjab, India
Tel: 09781925296
E-mail: [email protected]
Received December 10, 2014; Accepted December 23, 2014; Published February 02, 2015
Citation: Kaur M, Kamboj A, Rathour A, Saluja AK (2015) Isolation and Characterization of Constituents from the Leaves of Xanthium strumarium and their Evaluation for Antioxidant and Antimicrobial Potential. Nat Prod Chem Res 3:168. doi: 10.4172/2329-6836.1000168
Copyright: © 2015 Kaur M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Abstract

Xanthium strumarium L., belonging to the family compositae, is a medicinal plant commonly found as a weed, is widely distributed in North America, Brazil, China, Malasia and hotter part of India. The herb is traditionally used mostly in treating several ailments. The present research includes isolation and characterization of chemical constituents and in vitro evaluation of antioxidant potentials by three different assay methods of isolated constituents from leaves of Xanthium strumarium as the plant is an ingredient of various traditional preparations used in the treatment of various diseases. Three constituents (hexadecanoic acid, α-amyrin, 14-methyl-12,13-dehydro-sitosterol-heptadeconate) were isolated and the structures of these compounds have been established by spectroscopic methods (UV,1H-NMR, IR, MS). All these constituents were isolated from this plant for the first time. These chemical constituents showed significant antioxidant and antimicrobial activity in dose dependent manner by different assay methods. The result obtained in the present study indicates that leaves of Xanthium strumarium could be a potential source of natural antioxidant and antimicrobial. This also justified the traditional use of herb in preventing disease induced by oxidative stress and microorganism.

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