alexa Kinetics of Post-Exercise Excess CO2 Production and Substrate Oxidation in Two Dysglycemic and Euglycemic Older Women A Case Study.
ISSN: 2572-5629

Diabetes Case Reports
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Case Report

Kinetics of Post-Exercise Excess CO2 Production and Substrate Oxidation in Two Dysglycemic and Euglycemic Older Women A Case Study.

Andrei Gribok2*, William Rumpler2 and Loretta DiPietro1

1Department of Exercise Science, George Washington University School of Public Health and Health Services, Washington, DC, USA

2Food Intake and Energy Regulation Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, USDA, Beltsville, USA

Corresponding Author:
Andrei Gribok
Research Scientist, Food Intake and
Energy Regulation Laboratory, USDA, Beltsville, USA
(301) 504-5027
E-mail: agr[email protected]

Received date: March 08, 2016; Accepted date: May 22, 2016; Published date: May 24, 2016

Citation: Gribok A, Rumpler W, DiPietro L (2016) Kinetics of Post-Exercise Excess CO2 Production and Substrate Oxidation in Two Dysglycemic and Euglycemic Older Women A Case Study. Diabetes Case Rep 1:107. doi:10.4172/2572-5629.1000107

Copyright: © 2016 Gribok A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



We examine the case of post-exercise excess CO2 production and instantaneous substrate oxidation in two older women, one with impaired glucose tolerance and the other one is euglycemic. Both subjects stayed in the room-size calorimeter for 48 hours and performed three bouts of postprandial exercise on the second day. The instantaneous gas exchange rates have been estimated along with the instantaneous respiratory exchange ratio (RER) for the whole 48- hour experiment. The relative dynamics of O2 consumption and RER showed a greater reliance on the carbohydrate as energy source in dysglycemic woman than in euglycemic woman. Also, the rate of post-exercise excessive CO2 output, quantified as the time lag between peaks in O2 consumption and peaks in RER was found to be higher in dysglycemic woman suggesting heavier reliance on anaerobic metabolism during exercise. For the first time, results relating the excess post-exercise CO2 production and impaired glucose tolerance are presented.


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