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Laboratory Opossum (Monodelphis domestica) Model for Melanoma Chemoprevention | OMICS International | Abstract
ISSN: 1948-5956

Journal of Cancer Science & Therapy
Open Access

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Laboratory Opossum (Monodelphis domestica) Model for Melanoma Chemoprevention

Hareesh B. Nair* and John L. VandeBerg

Southwest National Primate Research Center, Texas Biomedical Research Institute, P.O. Box 760549, San Antonio TX 78245-0549, USA

*Corresponding Author:
Hareesh B. Nair, Ph.D
Southwest National Primate Research Center
Texas Biomedical Research Institute
7620 NW Loop 410, San Antonio TX 78227, USA
Tel: 210-258-9515
Fax: 210-258-9883
E-mail: [email protected]

Received date: July 20, 2012; Accepted date: July 23, 2012; Published date: July 25, 2012

Citation: Nair HB, VandeBerg JL (2012) Laboratory Opossum (Monodelphis domestica) Model for Melanoma Chemoprevention. J Cancer Sci Ther 4: xiv-xv. doi:10.4172/1948-5956.1000e110

Copyright: © 2012 Nair HB, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Melanoma is the most aggressive form of skin cancer. Developments in melanoma basic research and therapeutic interventions have advanced tremendously with help of animal models of this disease. Transgenic and knockout mice have provided a wide array of melanoma models, which are primarily used for studying molecular pathways and developing treatment strategies. To the best of our knowledge, there has been no natural animal model for research on chemoprevention of melanoma induced by UV light alone. In this editorial, we discuss the potential of the laboratory opossum (Monodelphis domestica) as a natural model for research on chemoprevention of melanoma.

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