Laryngeal Chondrosarcoma: A Case Report
Semmar A*, Mouden K, El Allam O, El Majjaoui S, Kebdani T and Benjaafar N
Department of Radiotherapy, National Institute of Oncology, Morocco
- Corresponding Author:
- Semmar A
National Institute of Oncology Morocco
Tel: 06 66 18 34 45
E-mail: [email protected]
Received December 18, 2015; Accepted March 25, 2016; Published March 31, 2016
Citation: Semmar A, Mouden E, El Allam O, El Majjaoui S, Kebdani T, et al. (2016) Laryngeal Chondrosarcoma: A Case Report. J Clin Case Rep 6:757. doi:10.4172/2165-7920.1000757
Copyright: © 2016 Semmar A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Introduction: Laryngeal chondrosarcoma is a rare tumor. It mainly develops in cricoid cartilage, surgery is the treatment of choice. His prognosis is good. Case Report: A 55 year old man, non-smoking, was diagnosed with grade 2 laryngeal chondrosarcoma. Surgical treatment consisted of a total laryngectomy with bilateral neck dissection. Radiation therapy on the tumor bed was performed at a dose of 66 Gy in 33 fractions of 2 Gy once daily for 7 weeks. The follow-up of this patient is 12 months and his ECOG is 0. Discussion: Laryngeal chondrosarcoma is a rare tumor, It mainly develops in cricoid cartilage. It produces dyspnea, dysphagia, odynophagia, hoarseness, and airway obstruction. CT scan is the method of choice for studying the larynx. Endoscopy enables biopsy, which should be profound as the tumor develops at the submucosal. Histopathological examination showed immature chondrocytes with variable cytonuclear abnormalities. There are three grades of severity: Grade 1, 2, 3 of laryngeal chondrosarcomas. Surgery is the treatment of choice. Chondrosarcoma is considered poorly sensitive to radiation therapy. Chemotherapy has no role in this indication. Prognosis depends upon histologic grade and quality of exeresis. Conclusion: Laryngeal chondrosarcoma is a rare tumor, with slow growth and insidious clinical picture; Surgery is the treatment of choice, prognosis is generally good, and basically dependent on histologic grade.