alexa Late Onset of Thoracic Aortic Disease Events after Abdominal Aortic Aneurysm Repair: Effect on Survival and Possible Associated Factors
ISSN: 2329-9495

Angiology: Open Access
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Research Article

Late Onset of Thoracic Aortic Disease Events after Abdominal Aortic Aneurysm Repair: Effect on Survival and Possible Associated Factors

Takuya Matsumoto1*, Eisuke Kawakubo1, Daisuke Matsuda1, Takeshi Takano1, Jun Okadome1, Koichi Morisaki1, Ryota Fukunaga1, Haidi Hu1, Junji Kishimoto2, Tomoko Ohkusa3, Toshihiro Onohara1 and Yoshihiko Maehara1

1Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

2Department of Research and Development of Next Generation Medicine Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan

3Kirameki Project Career Support Center, Kyushu University Hospital, Japan

*Corresponding Author:
Takuya Matsumoto
Department of Surgery and Science
Graduate School of Medical Sciences, Kyushu University
3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan
Tel: +81-92-642-5466
Fax: +81-92-642-5462
E-mail: [email protected]

Received Date: February 25, 2014; Accepted Date: March 28, 2014; Published Date: April 04, 2014

Citation: Matsumoto T, Kawakubo E, Matsuda D, Takano T, Okadome J et al. (2014) Late Onset of Thoracic Aortic Disease Events after Abdominal Aortic Aneurysm Repair: Effect on Survival and Possible Associated Factors. Angiol 2:126. doi:10.4172/2329-9495.1000126

Copyright: © 2014 Matsumoto T, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

We investigated the possible relation between thoracic aortic disease events and long-term survival in patients after open Abdominal Aortic Aneurysm (AAA) repair, as well as factors associated with event occurrence. Pre-AAArepair demographic, comorbid, and laboratory variables in 48 patients who had an aortic dissection or thoracic aortic aneurysm up to 25 years after AAA repair were compared with the same variables in 522 patients without such an event. Survival rates at 5 and 10 years were 87% and 53%, respectively, in patients with a thoracic aortic event and 74% and 56% in those without an event (P=.7). Multivariate analysis showed that the risk of thoracic aortic events was increased by a high hemoglobin level, a high Fibrinogen Degradation Product (FDP) level, and a larger AAA diameter. The only factors significantly associated with thoracic aortic events were an AAA diameter of ≥ 55 mm and a high FDP level.

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