Latest Update on Pharmacological Activities of 1,3,4-Oxadiazole DerivativesBasant Kumar1, Arvind Kumar1, Alok Kumar Beheraand1 and Vinit Raj2*
- *Corresponding Author:
- Vinit Raj
Department of Pharmaceutical Sciences
Babasaheb Bhimrao Ambedkar University
Vidya Vihar, Rai Bareli Road
E-mail: [email protected]
Received date: October 30, 2015; Accepted date: February 05, 2016; Published date: February 09, 2016
Citation: Kumar B, Kumar A, Beheraand AK, Raj V (2016) Latest Update on Pharmacological Activities of 1,3,4-Oxadiazole Derivatives. J Cell Sci Ther 7:233. doi:10.4172/2157-7013.1000233
Copyright: © 2016 Kumar B, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Heterocyclic compounds have been an interesting area for the study of synthesis and biological activity of novel oxadiazole derivatives for a long time. Heterocyclic compounds possess diverse biological properties that have led to intense study and research of these compounds. One of these compounds 1,3,4-Oxadiazole is a versatile heterocyclic nucleus is a novel molecule which attract the medicinal chemist to search a new therapeutic molecule. 1,3,4-oxadizole exhibited a wide range of biological activities which includes antimicrobial activity, anti-tubercular, anticonvulsant, antidiabetic, anti-allergic, enzyme inhibitors, anti-HIV activity, antipyretic activity, Immunosuppressive activity, Spasmolytic Activity, antioxidant activity, Anti-Alzheimer’s activity cardiovascular acivity, anti-inflammatory, anti-tumor activity, insecticidal activity, CGRP receptor antagonists, anti-anthelmintic activities. Results of various derivatives of different oxadiazole and their substitutions with diverse biological activities are reviewed in present article.