alexa Lipid Emulsion as First Line Treatment in Ropivacain In
ISSN: 2167-0846

Journal of Pain & Relief
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Case Report

Lipid Emulsion as First Line Treatment in Ropivacain Induced Neurologic Toxicity

Evans Marc S* and Fournier Roxane
Department of Anesthesiology, Pharmacology and Intensive Care, University Hospitals of Geneva, Switzerland
Corresponding Author : Evans Marc S, MD
Department of Anesthesiology
Pharmacology and Intensive Care
University Hospitals of Geneva, Switzerland
Tel: +41223823311
E-mail: [email protected]
Received December 06, 2012; Accepted March 30, 2012; Published April 14, 2012
Citation: Evans Marc S, Roxane F (2012) Lipid Emulsion as First Line Treatment in Ropivacain Induced Neurologic Toxicity. J Pain Relief 1:107. doi: 10.4172/2167-0846.1000107
Copyright: © 2012 Evans Marc S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


A 67 year old female patient presented with new neurological deficits (clonic movements, progressive confusion, dysarthria) and hemodynamic instability (hypotension, sinus tachycardia) immediately after uneventful performance of a sciatic block. Prompt infusion of a 100 ml intralipid emulsion in addition to a single bolus of 100 mcg phenylephrine reversed these signs within less than five minutes. Subsequently she remained hemodynamically stable and her neurological status returned to baseline. In absence of further signs of toxicity, the continuous intralipid infusion was interrupted.

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