LIPID Profile and Growth Indicators among OffspringÂ’s of Diabetic Parents in Karachi, PakistanMeraj Rahim1*, Mariam Rahim2, Masood Anwar Qureshi1, Shaheen Sharafat3, Zaman Shaikh4, Munim Abdul Rahim5 and Mubashir Zafar6
- *Corresponding Author:
- Dr Meraj Rahim
Assistant Professor of Physiology
Department of Physiology
Dow University of Health Sciences, Karachi, Pakistan
E-mail: [email protected]
Received date: June 09, 2014; Accepted date: September 26, 2014; Published date: October 06,2014
Citation: Rahim M, Rahim M, Qureshi MA, Sharafat S, Shaikh Z, et al. (2014) LIPID Profile and Growth Indicators among Offspring’s of Diabetic Parents in Karachi, Pakistan. J Diabetes Metab 5:443 doi: 10.4172/2155-6156.1000443
Copyright:2014 Rahim M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Background: Type 2 diabetes mellitus has become a universal problem. Globally 80% of lower and middle income countries are suffering from diabetes. Different studies show that offspring from diabetic parents growth indicators were disturbed the lipid profile and growth indicators. The objective of the study was to determine the levels of lipid profile and growth indicators among offspring of diabetic parents.
Material and methods: Cross sectional study was done. Total 180 subjects were recruited from Dow university of Health sciences and classified as both parents were diabetic (BDP), Single Parents Diabetic (SDP) and no parents were diabetic (NDP). The Growth indicators lipid profile was measured. The analyst concentration of Lipids was analyzed by The Roche Hitachi Analyzer 902 Automated Analyzer automatically .Fasting blood sugar levels was determined by glucose oxidase.
Results: Those offspring who gave history of diabetes in parents had their growth indicators and Lipid Profile were disturbed or raised when compared with non -diabetic parents. 25.6%, 5.6% and 5.6% of offspring belongs to Both Parents Diabetic (BDP), Single Diabetic Parents (SDP) and Not Diabetic Parents (NDP) respectively have obese. Similar lipid profile indicators also raised as More BDP and SDP subjects had high cholesterol (>200 mg/dL) than NDP (76.9% and 29.6% versus 10% respectively), More BDP and SDP subjects had high cholesterol (>150 mg/ dL) than NDP (23.1% and 2.8% versus 0% respectively). More BDP and SDP subjects had high cholesterol (>130 mg/dL) than NDP (76.9% and 29.6% versus 15% respectively).
Conclusions: Lipid profiles of offspring were related to diabetic parent’s history. Early screening and change in lifestyle modification can be a preventive intervention for the risk of developing diabetes in future.