alexa Long-term Neuropsychological Outcome and Quality of Life in Perinatal Ischemic Stroke | OMICS International| Abstract

ISSN: 2472-100X

Journal of Pediatric Neurology and Medicine

  • Review Article   
  • J Pediatr Neurol Med 2016, Vol 1(2): 2
  • DOI: 10.4172/2472-100x.1000104

Long-term Neuropsychological Outcome and Quality of Life in Perinatal Ischemic Stroke

Agnese Suppiej1*, Annalisa Traverso1, Laura Baggio1, Ambra Cappellari1, Paolo Simioni2, Mario Ermani3, Stefano Sartori1 and Elisa Cainelli1,4
1Child Neurology and Clinical Neurophysiology, Pediatric University Hospital, Padua, Italy
2Emophilia Center, Clinica Medica II, Department of Medical and Surgical Sciences, Padua, Italy
3Bio statistical Unit, Department of Neurosciences, University of Padua, Italy
4Lifespan Cognitive Neuroscience Laboratory (LCNL), Department of General Psychology, University of Padua, Italy
*Corresponding Author : Agnese Suppiej, Child Neurology and Clinical Neurophysiology, Pediatric University Hospital, Via Giustiniani, 3, 35100 Padua, Italy, Tel: 0039-49-8218094, Fax: 0039-49-8213509, Email: [email protected]

Received Date: Oct 16, 2015 / Accepted Date: Feb 01, 2016 / Published Date: Feb 08, 2016

Abstract

Background: Perinatal arterial ischemic stroke is an established risk factor for neuromotor and cognitive sequelae, but little is known about long-term neuropsychological implications. We aimed to evaluate long-term neuropsychological outcome and its effect on life quality in children with history of perinatal arterial ischemic stroke.

Methods: Seventeen children with history of perinatal arterial ischemic stroke, selected from the institutional cerebrovascular registry, were recruited for this study. Outcome was investigated using a battery of standardized neuropsychological tests and PedsQL questionnaire. A neuropsychological composite score (Cognitive Index) was calculated taking into account impaired performances.

Results: 47% of the patients had impaired Cognitive Index. Neuropsychological functions involved included: language, visuo-motor and executive functions, visual selective attention, with sustained attention as the most affected (59% of patients). Impairment in Cognitive Index was significantly associated with poor quality of life as perceived by parents.

Conclusion: In conclusion, minor impairments, such as neuropsychological deficits, can frequently occur in children with history of perinatal arterial ischemic stroke and may affect quality of life.

Keywords: Cognitive; IQ; Neonatal stroke; Arterial stroke; Cerebrovascular

Citation: Suppiej A, Traverso A, Baggio L, Cappellari A, Simioni P, et al. (2016) Long-term Neuropsychological Outcome and Quality of Life in Perinatal Ischemic Stroke. J Pediatr Neurol Med 1: 104. Doi: 10.4172/2472-100x.1000104

Copyright: ©2016 Suppiej A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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