Long-term Neuropsychological Outcome and Quality of Life in Perinatal Ischemic Stroke
- *Corresponding Author:
- Agnese Suppiej
Child Neurology and Clinical Neurophysiology
Pediatric University Hospital, via Giustiniani
3, 35100 Padua, Italy
E-mail: [email protected]
Received date: October 16, 2015; Accepted date: February 01, 2016; Published date: February 08, 2016
Citation: Suppiej A, Traverso A, Baggio L, Cappellari A, Simioni P, et al. (2016) Long-term Neuropsychological Outcome and Quality of Life in Perinatal Ischemic Stroke. J Pediatr Neurol Med 1:104. doi:10.4172/2472-100X.1000104
Copyright: © 2016 Suppiej A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Background: Perinatal arterial ischemic stroke is an established risk factor for neuromotor and cognitive sequelae, but little is known about long-term neuropsychological implications. We aimed to evaluate long-term neuropsychological outcome and its effect on life quality in children with history of perinatal arterial ischemic stroke. Methods: Seventeen children with history of perinatal arterial ischemic stroke, selected from the institutional cerebrovascular registry, were recruited for this study. Outcome was investigated using a battery of standardized neuropsychological tests and PedsQL questionnaire. A neuropsychological composite score (Cognitive Index) was calculated taking into account impaired performances. Results: 47% of the patients had impaired Cognitive Index. Neuropsychological functions involved included: language, visuo-motor and executive functions, visual selective attention, with sustained attention as the most affected (59% of patients). Impairment in Cognitive Index was significantly associated with poor quality of life as perceived by parents. Conclusion: In conclusion, minor impairments, such as neuropsychological deficits, can frequently occur in children with history of perinatal arterial ischemic stroke and may affect quality of life.