alexa Low Intensity (0.2T) Static Magnetic Field for Dispersi
ISSN: 2155-9562

Journal of Neurology & Neurophysiology
Open Access

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Research Article

Low Intensity (0.2T) Static Magnetic Field for Dispersing Nucleus Ankyrin G in Human Cultured Glioblastoma Cells

Seung Chan Kim1*, Wooseok Im2 and Beom Jin Kim3

1Medical School and College of Medicine, Yonsei University, Seoul, Republic of Korea

2Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea

3Department of Mathematics, Yonsei University, Seoul, Republic of Korea

Corresponding Author:
Seung Chan Kim
Medical School and College of Medicine
Department of Integrated OMICS for Biomedical Sciences (World Class University Program)
The School of Graduate Studies, Yonsei University
Yonsei-ro 50, Shinchon-dong, Seodaemoon-gu, Seoul, Republic of Korea
Tel: +82-2-6245- 2835
Fax: +82-2-6245-2835
E-mail: [email protected]

Received date: April 20, 2017; Accepted date: May 31, 2017; Published date: June 07, 2017

Citation: Kim SC, Im W, Kim BJ (2017) Low Intensity (0.2T) Static Magnetic Field for Dispersing Nucleus Ankyrin G in Human Cultured Glioblastoma Cells. J Neurol Neurophysiol 8:429. doi:10.4172/2155-9562.1000429

Copyright: © 2017 Kim SC, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Biomagnetism is one of important biotechnology fields for manipulation of cell lines. However, its peri-cellular level regulation, upon stimulation is not fully developed. Glioblastoma U87 and U251 represent a malignant model in rapid growing cancer. We focused in cellular level dispersion of static magnetic fields (0.2T=2000 ± 600 Gauss), using its fast growing properties. As a result, cytoskeletal protein nuclear Ankyrin G was dispersed. Membrane barriers in TEM microscopy indicated the membranous apparatus change. Our findings bring an insight that static magnetic stimulation creates a specified cytoplasmic intracellular pattern

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