Immunogenetics: Open Access
Open Access

Abstract

Lymphoid Seeding in the Thymus: A New Function for Ephb2 and Ephb3

David Alfaro, Javier García-Ceca, Sara Montero-Herradón and Agustín G. Zapata

We have found that the lack of EphB2 or EphB3 courses with decreased proportions of early thymic progenitors seeding the adult thymuses of EphB-deficient mice. The origin of these deficiencies is commented on the basis of profound alterations observed in the thymic epithelium of these mutant mice.