alexa Male Infertility and Klinefelter Syndrome (47, XXY)
ISSN: 2165-7920

Journal of Clinical Case Reports
Open Access

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Case Report

Male Infertility and Klinefelter Syndrome (47, XXY)

Paul L Cummins*, Connor Harrity, David J Walsh and Kevin J Marron
Division of Reproductive Endocrinology & Infertility, Sims IVF/The Sims Institute, Dublin, Ireland
Corresponding Author : Paul L Cummins
Division of Reproductive Endocrinology & Infertility
Sims IVF/The Sims Institute, Dublin, Ireland
Tel: +353 (0) 1 208 0710
Fax: +353 (0) 1 208 0715
E-mail: [email protected]
Received: September 29, 2015; Accepted: November 19, 2015; Published:November 26, 2015
Citation: Cummins PL, Harrity C, Walsh DJ, Marron KJ (2015) Male Infertility and Klinefelter Syndrome (47, XXY). J Clin Case Rep 5:641. doi:10.4172/2165-
Copyright: © 2015 Cummins PL, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits
unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Klinefelter syndrome is a chromosomal condition that affects male physical and cognitive development. The symptoms associated with KS vary greatly and many males with KS are never diagnosed or treated. Affected individuals typically have small testes that do not produce as much testosterone as usual. Reduced testosterone can impact reproductive maturation greatly and can lead to delayed or incomplete puberty, breast enlargement (gynecomastia), reduced facial and body hair, and an inability to have biological children (infertility). Puberty is a time of rapid physical and psychological change, and hormone replacement treatment can successfully limit and reduce the symptoms of KS. This case report encompasses a routine fertility evaluation in which a 38 year old Caucasian male was diagnosed with Klinefelter Syndrome (KS) and pronounced infertile. The case highlights the relative lack of awareness surrounding KS and the options which may enable KS males to produce healthy offspring.


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