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Malignant Fibrous Histiocytoma - An Unusual Transformation from Benign to Malignant | OMICS International | Abstract
ISSN: 1948-5956

Journal of Cancer Science & Therapy
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Research Article

Malignant Fibrous Histiocytoma - An Unusual Transformation from Benign to Malignant

Ashima Bali1*, Mohit Pal Singh2, Padmavathi 3, Manisha Khorate4, Junaid Ahmed5

1Post-Graduate Student, Department Of Oral Medicine & Radiology, Pacific Dental College & Hospital, Udaipur, Rajasthan

2Reader, Department of Oral Medicine & Radiology, Pacific Dental College & Hospital, Udaipur, Rajasthan

3Professor, Department of Oral Medicine & Radiology, Pacific Dental College & Hospital, Udaipur, Rajasthan

4Senior Lecturer, Department of Oral Medicine & Radiology, Pacific Dental College & Hospital, Udaipur, Rajasthan

5Professor & Head of the Department, Department Of Oral Medicine & Radiology, Pacific Dental College & Hospital, Udaipur, Rajasthan

*Corresponding Author:
Dr. ASHIMA BALI, Post-Graduate Student,
Department Of Oral Medicine & Radiology,
Pacific Dental College & Hospital,
Debari, Udaipur, Rajasthan,
E-mail: [email protected]

Received Date: March 10, 2010; Accepted Date: April 06, 2010; Published Date: April 06, 2010

Citation: Bali A, Singh MP, Padmavathi, Khorate M, Ahmed J (2010) Malignant Fibrous Histiocytoma - An Unusual Transformation from Benign to Malignant. J Cancer Sci Ther 2: 053-057. doi:10.4172/1948-5956.1000023

Copyright: © 2010 Bali A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Background: Malignant Fibrous Histiocytoma (MFH) is one of the most common soft tissue sarcoma in adults and typically arises in the soft tissues of the extremities and retroperitoneum. The head and neck region are seldom involved accounting for 3 – 8.5% of the cases. In the superficial sites such as skin, MFH may behave in a benign fashion despite the high grade appearing and fast growing tumor cells, with a reported incidence of malignant transformation around 1%. Case Description: A 72 year old male patient reported to the Department of Oral Medicine & Radiology with a chief complaint of recurrent pain and swelling over the upper lip and nose region which was surgically drained a month back. This was the third occurrence of the swelling over the past 13 years. In the past 2 episodes, he was surgically treated for Benign Fibrous Histiocytoma (BFH). Surgical procedure and histopathological report confirmed malignant transformation into MFH in the recent episode. Conclusion and Clinical Implications: This publication aims to highlight the possibility of malignant transformation of benign fibrous histiocytoma and the importance of long term followup.

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