alexa Management of Diabetic Foot Infections with Appropriate
ISSN: 2329-910X

Clinical Research on Foot & Ankle
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Review Article

Management of Diabetic Foot Infections with Appropriate Use of Antimicrobial Therapy

Afsaneh Alavi1*, Mazen S Bader2 and R Gary Sibbald3
1 Department of Medicine (Dermatology), Women’s College Hospital, University of Toronto, Toronto, Ontario, Canada
2 Department of Medicine, Division of infectious diseases, Hamilton Health sciences, Juravinski hospital and Cancer Centre, Hamilton, Ontario, Canada
3 Department of Medicine (Dermatology), University of Toronto, Toronto, Ontario, Canada
Corresponding Author : Afsaneh Alavi
Women’s College Hospital (main building) 76 Grenville Street (5th floor) Toronto
ON M5S 1B2, Canada
Tel: 416-323-6407
Fax: 416-323-6215
E-mail: [email protected]
Received December 11, 2013; Accepted January 26, 2013; Published February 05, 2014
Citation:Alavi A, Bader MS, Sibbald RG (2014) Management of Diabetic Foot Infections with Appropriate Use of Antimicrobial Therapy. Clin Res Foot Ankle S3: 010. doi:10.4172/2329-910X.S3-010
Copyright: © 2014 Alavi A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Up to 25% of patients with diabetes will develop a foot ulcer during their lifetime with a 50-70% recurrence rate over the ensuing 5 year. Additionally more than 50% of patients with a diabetic foot ulcer (DFU) develop a diabetic foot infection (DFI). DFI remains a challenge to manage because of coexisting immunopathy. Antibiotic therapy is the main stay of treatment for patients with deep and surrounding tissue infection. A multidisciplinary approach is required with the focus on the comprehensive patient assessment, vascular assessment with revascularization, proper offloading devices and use of appropriate antimicrobials. Wound care professionals have a unique position to lessen the inappropriate use of antimicrobials.


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