Managing Argatroban in Non-Obstructive Thrombosis of Mechanical Mitral Valve in Heparin Induced Thrombocytopenia Type II: A Case ReportBouchot O1, Vanzetto G1, Casset C1 and Marlu R2*
- *Corresponding Author:
- Marlu R,
Hemostasis Unit, University Hospital, Grenoble, France
E-mail: [email protected]
Received date: October 15, 2016; Accepted date: November 22, 2016; Published date: November 26, 2016
Citation: Bouchot O, Vanzetto G, Casset C, Marlu R (2016) Managing Argatroban in Non-Obstructive Thrombosis of Mechanical Mitral Valve in Heparin Induced Thrombocytopenia Type II: A Case Report. J Clin Case Rep 6:886. doi:10.4172/2165-7920.1000886
Copyright: © 2016 Bouchot O, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
We describe the successful management of argatroban in non-obstructive mechanical heart valve thrombosis in a context of heparin induced thrombocytopenia (HIT) type II. A 77-year-old female with permanent atrial fibrillation and mechanical heart valve developed an asymptomatic non obstructive thrombus of mechanical mitral heart valve diagnosed while she was under argatroban for acute HIT type II. Total disappearance of thrombus was achieved with a medical antithrombotic strategy combining increase of argatroban and VKA dosages and implementation of an antiplatelet treatment with aspirin.