Mangifera indica Extract (Vimang) Restored the Redox Balance in Type-1 Diabetic Patients
2.Second Degree Specialist in Laboratory Medicine and Master of Infectious Diseases, Institute of Medical Sciences, Carlos J Finlay, Camaguey, Cuba
- *Corresponding Author:
- MCs Dalyla Alonso Rodriguez
Dr. Eduardo Agramonte Pina
Provincial Pediatric Teaching Hospital
E-mail: [email protected]
Received Date: November 21, 2011; Accepted Date: January 12, 2012; Published Date: January 16, 2012
Citation: Alonso Rodriguez MD, Moreno Tellez DE, Medina Ali FE, Sanchez Morell DI (2012) Mangifera indica Extract (Vimang) Restored the Redox Balance in Type-1 Diabetic Patients. Biochem & Anal Biochem 1:107. doi:10.4172/2161-1009.1000107
Copyright: © 2012 Alonso Rodriguez MD, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
In diabetes mellitus, atherosclerosis is early, rapid, and widespread, affecting the dyslipoproteinemia secondary to hyperglycemia, lipoproteins glycosylation produced changes, making them more atherogenic and generate free radicals that cause apoprotein oxidation of lipids and macromolecules nearby, we decided to evaluated the presence of oxidative stress in children with Diabetes mellitus type-1 and demonstrated the need for antioxidants as part of drug therapy of this disease. Thirty ambulatory patients of Endocrinology were selected between 6 to 12 years of age, who had been suffering from Diabetes mellitus type-I since 3 years ago. Under their informed consent of the selected group the seric levels of antioxidant was tested: uric acid, vitamin C, bilirrubin, ceruloplasmin, albumin and cholesterol, LDL- cholesterol, HDL-cholesterol, triglycerides, oxidized LDL, Vimang tablets (300 mg/24 h) was supplied for three month, and the same tests were repeated every month. Data was processed by means of descriptive statistics methods, with of absolute and relative frequency distribution, performing a hypothesis test for paired observations.