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ISSN: 2165-8048

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Review Article

Markers of Inflammation and Rheumatology Tests–An Update for Internists

Maria Antonelli*, Bassam Alhaddad, Stanley Paul Ballou and Irving Kushner
Division of Rheumatology, Department of Medicine, Case Western Reserve University/MetroHealth Medical Center, Cleveland, Ohio, USA
*Corresponding Author : Maria Antonelli
Division of Rheumatology
Department of Medicine
Case Western Reserve University/MetroHealth Medical Center
Cleveland, Ohio, USA
Tel: 216-778-5154
Fax: 216-778-8376
E-mail: [email protected]
Received May 22, 2014; Accepted June 28, 2014; Published July 04, 2014
Citation: Antonelli M, Alhaddad B, Ballou SP, Kushner I (2014) Markers of Inflammation and Rheumatology Tests–An Update for Internists. Intern Med 4:162. doi:10.4172/2165-8048.1000162
Copyright: © 2014 Antonelli M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Importance: The rapid proliferation of laboratory tests related to rheumatology, the recent interest in C-reactive protein as a possible marker for cardiovascular disease risk, and the need to contain the costs of medical care by avoiding unnecessary testing have indicated the need for a review of these tests aimed at general internists. Objective: To provide internists with guidance for when to use specific rheumatology related laboratory tests. Evidence Review: Literature reviews as well as important rheumatology references were appraised in order to give an updated review of the rheumatology laboratory tests included in this review. Findings: Certain rheumatology tests should be employed when an internist suspects a particular autoimmune or connective tissue disease. Conclusions and Relevance: A detailed review of symptoms and examination is of primary importance, while laboratory tests usually serve to support or argue against possible diagnoses.

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