alexa Maternal Gut Microbes Control Offspring Sex and Survival
ISSN: 2329-8901

Journal of Probiotics & Health
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Maternal Gut Microbes Control Offspring Sex and Survival

Yassin M Ibrahim1, Sean M Kearney1,2, Tatiana Levkovich1, Alex Springer1,2, Sheyla Mirabal1, Theofilos Poutahidis1,3, Bernard J Varian1, Jessica R Lakritz1, Eric J Alm2,4 and Susan E Erdman1*
1Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
2Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
3Laboratory of Pathology, Faculty of Veterinary Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece
4Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
These first authors contributed equally to the preparation of the manuscript
Corresponding Author : Susan Erdman
Division of Comparative Medicine
Massachusetts Institute of Technology
Cambridge, Massachusetts, USA
Tel: 617-252-1804
Fax: 508-435-3329
E-mail: [email protected]
Received August 08, 2014; Accepted September 16, 2014; Published September 23, 2014
Citation: Ibrahim YM, Kearney SM, Levkovich T, Springer A, Mirabal S, et al. (2014) Maternal Gut Microbes Control Offspring Sex and Survival. J Prob Health 2:120. doi:10.4172/2329-8901.1000120
Copyright: © 2014 Ibrahim YM, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
 

Abstract

Sex outcome and maternal investment in progeny are important predictors of reproductive success. While
environmental factors appear to influence these processes, there is little evidence to date of a direct role for gut
commensals. Here we show that the reproductive outcomes (sex and survival) of mouse litters depend on signals
conveyed through the microbiome. We discover that transient treatment of mouse mothers with specific microorganisms
increases the absolute survival of offspring and skews offspring sex ratios via an endocrine-dependent
mechanism requiring the neurophysiological hormone oxytocin. The implication of maternal oxytocin levels suggests
that commensal microbes may have a broad role in modulating host endocrine and neurological pathways

Keywords

Share This Page

Additional Info

Loading
Loading Please wait..
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords