alexa Maternal Risk Factors, Complications and Outcome of Very Low Birth Weight Babies: Prospective Cohort Study from a Tertiary Care Centre in Odisha | OMICS International | Abstract
ISSN: 2167-0897

Journal of Neonatal Biology
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Research Article

Maternal Risk Factors, Complications and Outcome of Very Low Birth Weight Babies: Prospective Cohort Study from a Tertiary Care Centre in Odisha

Nandini Naskar, Arakhita Swain*, Kedar Nath Das and Abhaya Kumar Patnayak
Department of Pediatrics and Obstetrics and Gynecology, SCB Medical College and Hospital, Cuttack: 753007, Odisha, India
Corresponding Author : Dr. Arakhita Swain
Associate Professor in Paediatrics, “Sandhya Bhawan”
Plot- 535/1080, BJB Nagar, Bhubaneswar-751014, Odisha, India
Tel: 09437037373
E-mail: [email protected]
Received March 21, 2014; Accepted May 24, 2014; Published May 26, 2014
Citation: Naskar N, Swain A, Das KD, Patnayak AB (2014) Maternal Risk Factors, Complications and Outcome of Very Low Birth Weight Babies: Prospective Cohort Study from a Tertiary Care Centre in Odisha. J Neonatal Biol 3:142. doi:10.4172/2167-0897.1000142
Copyright: © 2014 Naskar N et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Background: Last two decades have witnessed a steady improvement in the quality of perinatal care in India. Better understanding of the pathophysiology and newer treatment strategies like antenatal steroid, surfactant use, newer modes of ventilation and stringent aseptic measures have contributed to the improved survival of very low birth weight babies.

Methods: In a prospective cohort study conducted in a tertiary care center over two years period (October 2011- September 2013), 744 VLBW babies (birth weight <1500 g) were assessed for gestational age, maturity, maternal risk factors and administration of antenatal steroids. Morbidities like birth asphyxia, sepsis, jaundice, respiratory distress syndrome, intraventricular haemorrhage, necrotisingenterocolitis, apnoea, pulmonary haemorrhage and patent ductusarteriosus were noted. Screening for retinopathy of prematurity and hearing impairment was done. Outcome in terms of survival till discharge was recorded.

Results: Out of 744 VLBW babies, 496 (66.67%) survived till discharge. Maternal risk factors associated with birth of VLBW babies were primiparity (58.06%), poor socio economic status (40.86%), multiple gestations (36.83%), PROM (26.34%), hypertension (13.44%) and under nutrition (12.36%). Jaundice (43.31%), apnoea (26.34%), birth asphyxia (20.43%), RDS (19.89%) and sepsis (18.82%) were found to be significant morbidities. Mortality was higher among males (20.43%) than females (12.9%). None below 27 weeks of gestation and birth weight of 800 g survived. RDS was the main cause of death (46.15%) followed by birth asphyxia (23%), sepsis (19.2%) and IVH (11.5%). Antenatal steroid improved the survival (72.9%) and reduced the incidence of RDS, NEC and IVH. ROP was detected in 30.49% VLBW babies. 33.3 % of the survivors failed in the initial hearing screening.

Conclusions: Higher birth weight, gestational age, female sex and antenatal steroids improved survival amongst VLBW babies. Antenatal steroids reduced incidence of RDS, NEC and IVH when preterm delivery was inevitable. Judicial use of supplemental oxygen and blood products prevent development of ROP.

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