alexa Matrix Tablets from Algerian Lyophilized Berries (LB) (
ISSN: 2329-6836

Natural Products Chemistry & Research
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Research Article

Matrix Tablets from Algerian Lyophilized Berries (LB) (Arbutus unedo L.) Date (Phoenix dactylifera L.)

Tounsia Abbas-Aksil1*, Moussa Abbas2, Mohamed Trari3 and Salem Benamara1
1Research Laboratory in Food Technology (LRTA) Faculty of Engineering Science University M’hamed Bougara 35000 Boumerdès, Algeria
2Laboratory of Soft Technologies and Biodiversity (LTDVPMB/F S), University M’hamed Bougara 3500 Boumerdès, Algeria
3Labotory of Storage and Valorization of Renewable Energies, Faculty of chemistry (USTHB) BP 32-16111 El-Alia, Bab Ezzouar, Algeria
*Corresponding Author : Tounsia Abbas-Aksil
Research Laboratory in Food Technology (LRTA)
Faculty of Engineering Science University
M’hamed Bougara 35000 Boumerdès, Algeria
Tel: +213554637886
E-mail: [email protected]
Received: February 15, 2016; Accepted: February 22, 2016; Published: February 29, 2016
Citation: Abbas-Aksil T, Abbas M, Trari M, Benamara S (2016) Matrix Tablets from Algerian Lyophilized Berries (LB) (Arbutus unedo L.) Date (Phoenix dactylifera L.). Nat Prod Chem Res 4:207. doi:10.4172/2329-6836.1000207
Copyright: © 2016 Abbas-Aksil T, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
 

Abstract

The present study aimed to elaborate matrix tablets from powder mixture (2:1 ratio) of Algerian date (Phoenix dactylifera L.) fruit and lyophilized berries (Arbutus unedo L.) (LB), using the direct compression technique. In a first part, the physicochemical properties, including the X-ray diffraction, of individual powders and their mixture were determined. In the second step, the swelling, erosion and in vitro release rate characteristics of tablets were studied. The dissolution study of tablets is evaluated throughout the electric conductivity (EC) of surrounding medium (distilled water). Among the four tested models, namely zero-order, first-order, Higuchi and Korsmeyer-Peppas, the latter seems to be the most appropriate (R2=0.972-0.989) to describe kinetics of the ionic transfer whatever the applied temperature. Further, the activation energy (17.272 kJ/mol) related to the transfer mechanism is obtained from the Arrhenius plot with a correlation coefficient greater than 0.899. Globally, the physicochemical parameters of obtained tablets were found to be in compliance with the pharmacopoeial standards.

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