alexa Mean Platelet Volume is Increased in Patients with Atrial Septal Aneurysm | OMICS International | Abstract
ISSN: 2155-9880

Journal of Clinical & Experimental Cardiology
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Research Article

Mean Platelet Volume is Increased in Patients with Atrial Septal Aneurysm

Mehmet Demir1* and Canan Demir2
1Departments of Cardiology Bursa Yuksek Ihtisas Education and Research Hospital, Bursa, Turkey
2Deparments of Infectious Diseases Bursa Sevket Yılmaz Education and Research Hospital, Bursa, Turkey
Corresponding Author : Dr. Mehmet Demir
Departments of Cardiology Bursa Yuksek Ihtisas Education and Research Hospital
Yaseminpark sit. 4-E blok D:11 Osmangazi 16100, Bursa/Turkey
Tel: +90 224 2573328
E-mail: [email protected]
Received May 23, 2012; Accepted June 13, 2012; Published June 15, 2012
Citation: Demir M, Demir C (2012) Mean Platelet Volume is Increased in Patients with Atrial Septal Aneurysm. J Clin Exp Cardiolog 3:200. doi: 10.4172/2155-9880.1000200
Copyright: © 2012 Demir M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Abstract

Background: Systemic thromboembolism is a serious major complication in patients with Atrial Septal Aneurysm (ASA). However, the pathogenesis of thromboembolism in ASA is not fully understood. The aim of this study was to assess the Mean Platelet Volume (MPV), an indicator of platelet activation, in patients with ASA. Patients and Methods: The study group consisted of 40 patients with ASA. An age, gender, and body mass index-matched control group consisted of 30 healthy volunteers. All patients and control participants underwent echocardiographic examination. We measured the serum MPV values in patients and control participants. Results: Mean platelet volume was significantly higher among patients with ASA when compared with the control group (9.8 ± 1.1 vs 7.6 ± 0.8 fL, respectively; P < 0.001). Conclusion: We have shown that MPV was significantly elevated in patients with ASA compared to control participant.

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