alexa Measuring Workload of Clinical Trials: Transcultural Ad
ISSN: 2155-9627

Journal of Clinical Research & Bioethics
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Measuring Workload of Clinical Trials: Transcultural Adaptation and Validation to Portuguese Lanquage of Ontario Protocol Assessment Level (OPAL)

To read the full article Peer-reviewed Article PDF image


Introduction: The increase number of clinical protocols with different requirements and specificities, the demand for the quality of the data according to the good clinical practices evidence the need of an instrument capable of measuring the workload of clinical protocols, and to assist the management of research centers. The object of study is the instrument entitled the Ontario Protocol Assessment Level, created for measuring the workload of the research coordinator, focusing on the complexity of clinical protocols in oncology. Aim: To perform a transcultural adaptation and validation of the instrument in terms of the Portuguese language. Method: This is a methodological research, whose chosen scenario was the clinical research center of the Brazilian National Cancer Institute, located in Rio de Janeiro. The subjects were the clinical research coordinators. The research was approved by the ethics committee, under protocol 070066-12.50000.5274. Results: A significantly high degree of agreement between intra- and inter-observers was established; the agreement of the committee of specialists (the golden standard) was considered to be excellent (ICC>0.949) in both research periods (1 and 2); this score demonstrates a high level of validation. The analytical process confirmed that the tool score did not overestimate nor underestimate the evaluation of the committee of specialists. Conclusion: The instrument was considered valid and reliable based on the statistical tests performed. It provides the support required to calculate the workload generated by clinical protocols.


Share This Page

Additional Info

Loading Please wait..
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version