alexa Median Raphe Cyst–Clinical Report and Immunohistochemi
ISSN: 2155-9554

Journal of Clinical & Experimental Dermatology Research
Open Access

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Case Report

Median Raphe Cyst–Clinical Report and Immunohistochemical Analysis

Zoran Persec1, Jasminka Persec2, Tomislav Sovic1, Duje Rako2, Jasna Bacalja3, Zlatko Hrgovic4* and Roland Kaufmann5

1Department of Urology, University Hospital Dubrava, Zagreb, Croatia

2Anesthesiology, Reanimatology and Intensive Care Medicine Clinic, University Hospital Dubrava, Zagreb, Croatia

3Department of Pathology, University Hospital Dubrava, Zagreb, Croatia

4Department of Gynecology and Obstetrics, J.-W Goethe University School of Medicine, Frankfurt/M, Germany

5Department of Dermatology and Venereology, J.-W Goethe University School of Medicine, Frankfurt, Germany

*Corresponding Author:
Zlatko Hrgovic
Department of Gynecology
University Hospital Osijek
Croatia, Europe
Tel: 0049 69 293000
Fax: 0049 69 291697
E-mail: [email protected]

Received date: December 26, 2012; Accepted date: February 26, 2013; Published date: March 09, 2013

Citation: Persec Z, Persec J, Sovic T, Rako D, Bacalja J, et al. (2013) Median Raphe Cyst–Clinical Report and Immunohistochemical Analysis. J Clin Exp Dermatol Res S6:011. doi: 10.4172/2155-9554.S6-011

Copyright: © 2013 Persec Z, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Cysts of the median raphe are very rare. We describe a 20-year-old man with an asymptomatic nodule on the ventral surface of the penis. The nodule was surgically removed under local anaesthesia, and send to histological and immunohistochemical analisys. Immunohistologicaly epithelial cells apeared Cytokeratin-7 (CK7), Epithelial membrane antigen (EMA) positive and anti-S100 protein (S100), Cytokeratin-20 (CK20), smooth muscle actin (SMA) and carcinoembryonic antigen (CEA) negative. Hystological and immunohystochemical findings indicate median raphe cyst.

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