alexa Medicinal Plants of Israel: A Model Approach to Enable an Efficient, Extensive, and Comprehensive Field Survey | OMICS International| Abstract

ISSN: 2376-0214

Journal of Biodiversity, Bioprospecting and Development

  • Research Article   
  • J Biodivers Biopros Dev 2014, Vol 1(3): 134
  • DOI: 10.4172/2376-0214.1000134

Medicinal Plants of Israel: A Model Approach to Enable an Efficient, Extensive, and Comprehensive Field Survey

Gili Joseph1*, Mina Faran1, Ilya Raskin2, Mary Ann Lila3 and Bertold Fridlender1
1Department of Biotechnology, Hadassah Academic College, Jerusalem, Israel
2Department of Plant Biology and Pathology, Rutgers University, New Brunswick, NJ 08901, USA
3Department of Food Science, North Carolina State University, Kannapolis, NC, USA
*Corresponding Author : Gili Joseph, Department of Biotechnology, Hadassah Academic College, Jerusalem, Israel, Tel: 972544577095, Fax: 972774704270, Email: [email protected]

Received Date: Sep 28, 2014 / Accepted Date: Oct 21, 2014 / Published Date: Nov 03, 2014

Abstract

Background: Israel has a large variety of indigenous plants due to its unique geography, connecting three continents with different climate zones; however, local species have not been systematically screened.

Methods: Plant samples were collected during/immediately after the rainy season from eight climate zones. Following collection, extracts were created within 24 h. Field-deployable bioassays assessing 12 types of antidisease/health protection activity were performed within 48 hours using a rapid, accurate paradigm for bioexploration based on the Screen to Nature (STN) technique developed by the Global Institute of BioExploration (GIBEX). Plant extracts were assessed for medicinal activity on a scale of 0 (no activity) to 3 (most potent).

Results: More than 1,100 plant samples derived from 614 plants belonging to 85 families were screened. Approximately 60% belonged to 12 families, notably the Asteraceae, Fabaceae, Lamiaceaen and Brassicaceae families. About 60% of samples showed at least one high-potency bioactivity (3/3); 20 plants exhibited 3–4 anti-disease/health protection activities. Plants growing in areas with more extreme conditions showed more bioactivity compared to those in less harsh climates. Antibacterial and antifungal activity, capacity for glucosidase detection and inhibition, and antioxidant activity were most common; protozoa, roundworm, and flat worm lethality, activity for planaria regeneration, protease detection and inhibition, and anthocyanin were also seen. There were sixteen plant samples that exhibited activity in a dose response manner using the STN assays as well as in using the Minimum Inhibitory concentration tests.

Conclusions: The Screen to Nature (STN) technique enables rapid, accurate field-deployable screening of diverse plant species for multiple anti-infectious/health protection activities. By using this technique at least 16 plant samples were identified as plants with potential to serve as a source of biological material for medicinal purposes.

Keywords: Anti-infectious disease properties; Bioactivity; Bioexploration; Medicinal plants; Plant field survey; Screens-to-Nature

Citation: Joseph G, Faran M, Raskin I, Ann Lila M, Fridlender B (2014) Medicinal Plants of Israel: A Model Approach to Enable an Efficient,Extensive, and Comprehensive Field Survey. J Biodivers Biopros Dev 1: 134. Doi: 10.4172/2376-0214.1000134

Copyright: ©2014 Joseph G, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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