Mesenchymal Paradigm: Implications in MorphogenesisGheorghe S Dragoi*, Elena Patrascu, Ileana Dinca and Petru Razvan Melinte
Department of Anatomy, University of Medicine and Pharmacy of Craiova, Craiova, Dolj, Romania
- *Corresponding Author:
- Gheorghe S Dragoi
Department of Anatomy
University of Medicine and Pharmacy of Craiova
Ion Maiorescu Street 7, Craiova 200760, Dolj
E-mail: [email protected]
Received date: September 24, 2016; Accepted date: December 15, 2016; Published date: December 19, 2016
Citation: Dragoi GS, Patrascu E, Dinca I, Melinte PR (2016) Mesenchymal Paradigm: Implications in Morphogenesis. J Forensic Res 7: 358. doi:10.4172/2157-7145.1000358
Copyright: © 2016 Dragoi GS, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, whi`ch permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
A micro-anatomic study of mesenchyme involvement in the morphogenesis of human biosystem is intended. The research was carried out on 80 sagittal serial sections taken from a 12-week human fetus. Spatial distribution of mesenchyme within the gut tube, urogenital and endocrine systems was analyzed. The results are based on the assumption that there are two forms of mesenchyme if one takes into consideration the embryonic origin: mesenchyme originating from mesoderm (meso-mesenchyme) and mesenchyme originating from ectoderm (ectomesenchyme) within the neural crest. We believe that in the morphogenesis of human biosystem, the mesenchyme can be induced byphenotype changes or it can act as an inductor in other structures. The significance of mesenchyme space distribution and of its phenotype changes in pathology is discussed.