alexa Mesenchymal Stem Cells as a Potential Source of Hepatoc
ISSN: 2572-4916

Journal of Bone Research
Open Access

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Review Article

Mesenchymal Stem Cells as a Potential Source of Hepatocyte like Cells

Amira Othman1,2* and Mai Hassan3
1Faculty of Medicine, Helwan University, Cairo, Egypt
2Mansoura Research Center for Cord Stem Cells, Mansoura University, Mansoura, Egypt
3Faculty of Medicine, Mansoura University, Mansoura, Egypt
*Corresponding Author : Amira Othman
Al Sikka Al Hadid Al Gharbeya
Qism Helwan, Cairo Governorate, Egypt
Tel: +20 2 25541912
E-mail: [email protected]
Rec date: Feb 25, 2016; Acc date: Mar 11, 2016; Pub date: Mar 15, 2016
Citation: Othman A, Hassan M (2016) Mesenchymal Stem Cells as a Potential Source of Hepatocyte like Cells. J Bone Res 4:166.
Copyright: © 2016 Othman A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


The field of regenerative medicine is growing up rapidly in the last decades, the usage of cellular therapy such as stem cells start to grasp attention in many experimental and even clinical trial. In this article, we mainly concentrate on the potentiality of the mesenchymal stem cell (MSC) to differentiate into hepatocyte like cells, which can overcome the problem of donor’s shortage. MSC have been use lately in many in vitro and in vivo experiments, and have showed great capacity of multilinage differentiation, interestingly they have the capacity to differentiate into hepatocyte like cells. Currently many clinical trials started to involve the usage of self-MSC as a novel therapy for hepatic complication such as fibrosis or cirrhosis, which showed promising results in treatment of hepatic patients. MSC can be injected in hepatic patient to replace the cirrhotic liver, which gives a real hope for the hepatic patients as a reliable source for regeneration.


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